Origins of oocyte aneuploidy

L Stuppia - Oogenesis, 2013 - Springer
… aged mammalian oocytes show a deficiency of some major component of … in
mitochondria-derived ATP induced by oxidative stress causes a disassembly of mouse MII oocyte

Maternal diabetes and oocyte quality

Q Wang, KH Moley - Mitochondrion, 2010 - Elsevier
… in oocytes from diabetic mice, suggesting the impaired oocyte … a bipolar spindle and all
chromosomes align at the spindle … identified that the levels of ATP and TCA cycle metabolites are …

Effects of reactive oxygen species and mitochondrial dysfunction on reproductive aging

J Song, L Xiao, Z Zhang, Y Wang, P Kouis… - Frontiers in Cell and …, 2024 - frontiersin.org
… substance ATP into all cellular compartments through a … of oxidative damage, implies a
vicious cycle wherein impaired … In aged mice, MII oocytes were fertilized with significantly …

[HTML][HTML] Endometriosis is a cause of infertility. Does reactive oxygen damage to gametes and embryos play a key role in the pathogenesis of infertility caused by …

G Máté, LR Bernstein, AL Török - Frontiers in endocrinology, 2018 - frontiersin.org
impedes mitochondrial respiration, reducing the rate of ATP … of oxidative damage to oocytes
in endometriosis is comprised by aberrations in the organization of oocyte meiotic spindles

[HTML][HTML] The role of lifestyle and dietary factors in the development of premature ovarian insufficiency

AN Shelling, N Ahmed Nasef - Antioxidants, 2023 - mdpi.com
… In this review, we discuss the mechanisms of oxidative stress … amenorrhoea for at least 4
months, oestrogen deficiency and … to disrupt meiotic spindles in oocytes, which compromises …

[HTML][HTML] Age-associated lipidome changes in metaphase II mouse oocytes

HJ Mok, H Shin, JW Lee, GK Lee, CS Suh, KP Kim… - PLoS …, 2016 - journals.plos.org
oocytes declines with age, which negatively affectsspindle abnormalities, and mitochondrial
dysfunction [2–4]. … the exogenous oxidative stress condition used herein in mouse oocytes. …

[HTML][HTML] Reduction of oocyte lipid droplets and meiotic failure due to biotin deficiency was not rescued by restoring the biotin nutritional status

A Tsuji, Y Ikeda, M Murakami, Y Kitagishi… - … Research and Practice, 2022 - ncbi.nlm.nih.gov
… if a biotin deficiency affects the lipid metabolism in oocytes. … abnormal meiosis due to an ATP
deficiency [21]. Interestingly, it … diet, the oxidative stress-induced oocyte spindle defects and …

16 Origins of Oocyte Aneuploidy

L Stuppia - Oogenesis, 2012 - books.google.com
… decrease in mitochondria-derived ATP induced by oxidative stress causes a disassembly of
mouse MII oocyte spindles [30]. … Deficit of mitochondria-derived ATP during oxidative stress

Effect of a low ethanol concentration during in vitro maturation of bovine oocytes and subsequent embryo development

T Sato, M Hamazaki, Y Inoue, S Aoki, Y Koshiishi… - Theriogenology, 2023 - Elsevier
… of ethanol during in vitro maturation considerably affects oocyte metabolism and … in
mitochondria-derived ATP by opening the permeability transition pore induced a deficit in spindle

[PDF][PDF] The Role of Mitochondria in Oocyte Maturation. Cells 2021, 10, 2484

A Kirillova, JEJ Smitz, GT Sukhikh, I Mazunin - 2021 - academia.edu
During the transition from GV to MII oocytes at the late antral follicle stage, the … Deficit
of Mitochondria-Derived ATP during Oxidative Stress Impairs Mouse MII Oocyte Spindles