Clinical trials in male hormonal contraception
E Nieschlag - Contraception, 2010 - Elsevier
… on suppression of gonadotropins and spermatogenesis. All … on testosterone combined with
norethisterone, desogestrel, … antibodies, leads to reduction of sperm concentration but not …
norethisterone, desogestrel, … antibodies, leads to reduction of sperm concentration but not …
Male hormonal contraception: suppression of spermatogenesis by injectable testosterone undecanoate alone or with levonorgestrel implants in chinese men
WJ Bremner, PJ Yang, JK Amory, ES Gao, J Yang… - 2004 - digital.lib.washington.edu
… reductions in total and high-density lipoprotein (HDL) choles… and LNG implants leads to a
marked spermatogenic suppression in … Suppression of spermatogenesis with desogestrel and …
marked spermatogenic suppression in … Suppression of spermatogenesis with desogestrel and …
Twenty-one day administration of dienogest reversibly suppresses gonadotropins and testosterone in normal men
MC Meriggiola, WJ Bremner… - The Journal of …, 2002 - academic.oup.com
… DSG caused side effects, such as decreased high density … used, but the level of sperm
suppression was also significantly … combination with T to suppress spermatogenesis, it could offer …
suppression was also significantly … combination with T to suppress spermatogenesis, it could offer …
Drug insight: recent advances in male hormonal contraception
… years that the chronic administration of testosterone to a man suppresses sperm production.
… suppression of spermatogenesis beyond that achieved by TE alone or TE plus desogestrel, …
… suppression of spermatogenesis beyond that achieved by TE alone or TE plus desogestrel, …
Levonorgestrel implants (Norplant II) for male contraception clinical trials: combination with transdermal and injectable testosterone
ITG Gonzalo, RS Swerdloff, AL Nelson… - The Journal of …, 2002 - academic.oup.com
… spermatogenesis as LNG 500 μg/d while causing less weight gain and high-density lipoprotein
(HDL) cholesterol … Substituting desogestrel for LNG did not result in less suppression of …
(HDL) cholesterol … Substituting desogestrel for LNG did not result in less suppression of …
An effective hormonal male contraceptive using testosterone undecanoate with oral or injectable norethisterone preparations
A Kamischke, T Heuermann, K Krüger… - The Journal of …, 2002 - academic.oup.com
… decrease in high-density lipoprotein cholesterol and alkaline … sufficient suppression of
spermatogenesis with Desogestrel (… Therefore, we attribute the modest increase in PRL to a …
spermatogenesis with Desogestrel (… Therefore, we attribute the modest increase in PRL to a …
Male hormonal contraceptives
JK Amory, BD Anawalt - Expert Opinion on pharmacotherapy, 2001 - Taylor & Francis
… strated greater suppression of spermatogenesis than the WHO … enough testosterone to
adequately suppress circulating gona… have tested the combination of T plus desogestrel (DSG), a …
adequately suppress circulating gona… have tested the combination of T plus desogestrel (DSG), a …
Advances in male hormonal contraception
BD Anawalt, JK Amory - Annals of Medicine, 2001 - Taylor & Francis
… of exogenous testosterone (T) alone suggest that suppression of … is suppression of highdensity
lipoprotein cholesterol levels. … have tested the combination of T plus desogestrel (DSG), a …
lipoprotein cholesterol levels. … have tested the combination of T plus desogestrel (DSG), a …
Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis
PY Liu, RS Swerdloff, BD Anawalt… - The Journal of …, 2008 - academic.oup.com
… Caucasian men suppressed sperm output faster initially but … initial blood testosterone or
sperm concentration were also … of norethisterone (NET), oral desogestrel (DSG), implants of …
sperm concentration were also … of norethisterone (NET), oral desogestrel (DSG), implants of …
Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis
PY Liu, RS Swerdloff, PD Christenson, DJ Handelsman… - The Lancet, 2006 - thelancet.com
… shorter treatment duration, shorter-acting testosterone preparations, higher sperm concentrations
at baseline, faster suppression of spermatogenesis, and lower blood concentrations of …
at baseline, faster suppression of spermatogenesis, and lower blood concentrations of …