Identification of an immunostimulating protein from Mycobacterium leprae
N Mohagheghpour, MW Munn, RH Gelber… - Infection and …, 1990 - Am Soc Microbiol
… antibodies frompatients with leprosy but, more importantly, elicits T-lymphocyteresponses
from patients with leprosy that parallel their responses to whole M. Ieprae organisms. …
from patients with leprosy that parallel their responses to whole M. Ieprae organisms. …
[HTML][HTML] Diagnostic accuracy of tests using recombinant protein antigens of Mycobacterium leprae for leprosy: A systematic review
ALG de Oliveira, VG Fraga… - Journal of infection and …, 2020 - Elsevier
… antigens from Mycobacterium leprae for leprosy diagnosis. We … of leprosy (PADL), recombinant
culture filtrate protein-10 (rCFP-… leprae infection and the identification of leprosy patients. …
culture filtrate protein-10 (rCFP-… leprae infection and the identification of leprosy patients. …
Enhancing Sensitivity of Detection of Immune Responses to Mycobacterium leprae Peptides in Whole-Blood Assays
A Geluk, JJ van der Ploeg-van Schip… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
… Leprosy is a disabling and stigmatizing disease caused by infection with Mycobacterium
leprae. The … leprae antigens, whole blood of BT leprosy patients was stimulated for 24 h with …
leprae. The … leprae antigens, whole blood of BT leprosy patients was stimulated for 24 h with …
ML0405 and ML2331 Are Antigens of Mycobacterium leprae with Potential for Diagnosis of Leprosy
ST Reece, G Ireton, R Mohamath… - Clinical and vaccine …, 2006 - Am Soc Microbiol
… diagnosis based on antibody … of diagnosis. Using serological expression cloning with a
serum pool of untreated lepromatous leprosy (LL) patients, we identified 14 strongly reactive M. …
serum pool of untreated lepromatous leprosy (LL) patients, we identified 14 strongly reactive M. …
… of IFNγ and CXCL10 in whole blood assay detects Mycobacterium leprae infection but does not discriminate asymptomatic infection from symptomatic leprosy
EM Hungria, AA Freitas, MAA Pontes… - … and Infectious Disease, 2017 - Elsevier
… the diagnosis of paucibacillary (PB) leprosy, we evaluated a prototype in-tube WBA using
combinations of Mycobacterium leprae … , PB leprosy patients are negative in antibody detection …
combinations of Mycobacterium leprae … , PB leprosy patients are negative in antibody detection …
Mycobacterium leprae virulence-associated peptides are indicators of exposure to M. leprae in Brazil, Ethiopia and Nepal
K Bobosha, ST Tang… - Memórias do Instituto …, 2012 - SciELO Brasil
… of Mycobacterium leprae, as evidenced by stable leprosy incidence … , the development
of tools for the early diagnosis of M. … and culture filtrate protein 10. J Infect Dis 181: 1850-1854. …
of tools for the early diagnosis of M. … and culture filtrate protein 10. J Infect Dis 181: 1850-1854. …
Field-Evaluation of a New Lateral Flow Assay for Detection of Cellular and Humoral Immunity against Mycobacterium leprae
K Bobosha, EM Tjon Kon Fat… - PLoS neglected …, 2014 - journals.plos.org
… -PGL-I antibodies was tested using M. leprae-stimulated blood of leprosy patients and endemic
controls (… Recently, IFN-γ induced protein 10 (IP-10) was found useful for detection of M. …
controls (… Recently, IFN-γ induced protein 10 (IP-10) was found useful for detection of M. …
Postgenomic Mycobacterium leprae antigens for cellular and serological diagnosis of M. leprae exposure, infection and leprosy disease
A Geluk, MS Duthie, JS Spencer - Leprosy review, 2011 - leprosyreview.org
… Such tools for early diagnosis of M. leprae infection would facilitate informed decision …
have an increased risk to develop leprosy (eg contacts of leprosy patients). Consequently, such …
have an increased risk to develop leprosy (eg contacts of leprosy patients). Consequently, such …
Antigen discovery: a postgenomic approach to leprosy diagnosis
… Mycobacterium leprae, the etiologic agent of leprosy, has undergone a reductive … We
first investigated whether our candidates generated antibody responses in leprosy patients by …
first investigated whether our candidates generated antibody responses in leprosy patients by …
[HTML][HTML] Towards an immunodiagnostic test for leprosy
… MLP) that are restricted to Mycobacterium leprae, or of limited … of a useful test for detecting
infection by the leprosy bacillus, … -6 kDa) and CFP-10 (culture filtrate protein-10) [13], [14], …
infection by the leprosy bacillus, … -6 kDa) and CFP-10 (culture filtrate protein-10) [13], [14], …