Marine algal carotenoids inhibit angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial cells

P Ganesan, K Matsubara, T Sugawara… - Molecular and cellular …, 2013 - Springer
… composed of highly organized three-dimensional cords [29]. As … In this study, a further
indication of the anti-angiogenic activity … From our findings, it is also likely that development of diet-…

The contribution of tumor-associated macrophages in glioma neo-angiogenesis and implications for anti-angiogenic strategies

C Zhu, JM Kros, C Cheng, D Mustafa - Neuro-oncology, 2017 - academic.oup.com
… stalk cells during sprouting, with similar effects. (D) Putative direct contact interaction mechanisms
between TAMs and endothelial cellscancer growth and reduced tumor angiogenesis. …

Apigenin suppresses tumor angiogenesis and growth via inhibiting HIF-1α expression in non-small cell lung carcinoma

J Fu, W Zeng, M Chen, L Huang, S Li, Z Li… - … -Biological Interactions, 2022 - Elsevier
… not merely suppressed endothelial cells related motilities but … apigenin exhibited a perfect
anti-angiogenic effect in vitro and … And then we established a 3D co-culture of HUVECs and …

TNP-470 reduces glioblastoma angiogenesis in three dimensional GelMA microwell platform

DT Nguyen, Y Fan, YM Akay… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
… immigration of endothelial cells into a cancer spheroid during … tested the anti-angiogenic
effect of the angiogenesis inhibitor… endothelial cell growth and metastasis of human cancers, …

… and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis

K Gupta, P Gupta, R Wild, S Ramakrishnan, RP Hebbel - Angiogenesis, 1999 - Springer
… We conclude that (i) the anti-angiogenic activity of TSP is … Yet, angiogenesis and tumor
growth are dependent on … from endothelial cell heparan sulfate and the direct interaction of TSP …

Tumor angiogenesis: past, present and the near future

RS Kerbel - Carcinogenesis, 2000 - academic.oup.com
… in tumor angiogenesis and anti-angiogenic drug development, to … targeting the vascular
endothelial cells of newly formed, … of cut sections (slices) of blood vessels in three dimensional

Modelling of endothelial cell migration and angiogenesis in microfluidic cell culture systems

N Kuzmic, T Moore, D Devadas, EWK Young - … and modeling in …, 2019 - Springer
… When pro- and anti-angiogenic factors are imbalanced in … Our most recent system was
developed to study comigration … ) that modelled the 3D tubular structures of both endothelial-lined …

Potential role of natural compounds as anti-angiogenic agents in cancer

MK Shanmugam, S Warrier, AP Kumar… - Current vascular …, 2017 - ingentaconnect.com
… and delivering the drugs to the sites of tumor angiogenesis. … a project by targeting tumor
endothelial cells with angiogenic … attenuate the growth of HUVECs and tumor angiogenesis in a …

Tumor-endothelial cell three-dimensional spheroids: new aspects to enhance radiation and drug therapeutics

M Upreti, A Jamshidi-Parsian, NA Koonce… - Translational …, 2011 - Elsevier
… a murine endothelial cell line to model tumor endothelium for studying the antiangiogenic
, to investigate the multicellular interactions involved in tumor growth and angiogenesis, we …

Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell …

MG Marks, J Shi, MO Fry, Z Xiao, M Trzyna… - Biological and …, 2002 - jstage.jst.go.jp
… enhances the anti-angiogenic effect of the drug in rat aortic … ) whereas in our studies
angiogenesis was stimulated using … the CAM whereas in our studies growth factors were applied …