… Some studies have indicated that PARP inhibitor prevents the diabetes-induced elevation
in circulating nitrite levels in STZ-induced diabetes. It has been reported that PARP deficiency …

… It is worth noting that a similar mechanism in pancreatic islet cells could explain the
resistance of PARP-1 −/− mice to diabetes induced by the alkylating agent streptozotocin [ …

… - or high-dose fluoride, and P53-knockdown or poly-ADP-ribose polymerase-1 (PARP-1)
inhibition. The levels of PARP-1, P53, poly-ADP-ribose (PAR), apoptosis-inducing factor (AIF), …

… Mitochondria, commonly known as the powerhouse of the cell, play fundamental roles in
maintaining basic cellular functions. Mitochondria dysfunction under stress conditions facilitates …

… In this study, we have evaluated the involvement of nitrosative stress and poly-ADP ribosyl
polymerase (PARP) in diabetes induced neurobehavioral and neurochemical changes using …

… stress and activation of poly(ADP ribose) polymerase (PARP) play a role in the pathogenesis
… Poly (ADPribose) polymerase gene disruption renders mice resistant to cerebral ischemia. …

… dysfunction which contributes to atherosclerosis. Atherosclerosis and dyslipidemia are major
risk factors for cardio-cerebrovascular … 21, 34], suggesting diabetes-induced organ damage. …

… models of diabetes induced by … dysfunction in diabetic blood vessels (48). The possibility
of normalizing diabetic endothelial dysfunction using a specific of poly(ADP-ribose) polymerase …

… that accomplishes the transfer of ADP-ribose from their substrate β-… role of PARP1 in
inflammatory processes such as myocardial infarction, diabetes-induced endothelial dysfunction, …

… AP-1) mediate diabetes-induced fibronectin expression in the … to be facilitated by poly(ADP-ribose)
polymerase (PARP) (15)… The function of PARP is to transfer the ADP-ribose units from …