… illustrative case of a 60‐year‐old man with metastatic melanoma who presented with AKI
during treatment … asked questions concerning the diagnosis and management of renal irAEs in …

… The most common kidney side effect is acute kidney injury, … in immune checkpoint
inhibitor-induced acute kidney injury. The … checkpoint inhibitor classes in causing acute kidney …

… to diagnose because they may present as generalized symptoms, such as fatigue and
weakness, that can also be caused by the cancer itself. Here, we present an illustrative … treatment …

… Renal insufficiency CTLA-4 and PD-1 inhibitors have been associated with renal … nephritis,
and two cases of interstitial nephritis with renal failure confirmed by biopsy (one grade 3 and …

… In a retrospective series of 13 patients who underwent kidney biopsy at seven centers,
renal toxicity was diagnosed a median of 91 days after initiation of checkpoint inhibitor …

… drug suspension, renal biopsy, and/or immunosuppressive treatment. This short … management
of cancer patients with renal toxicity during treatment with immune checkpoint inhibitors…

… Immune checkpoint inhibitors (ICPi) are a novel and promising … Immune checkpoint inhibitors
(ICPi) are a novel and … antibodies that inhibit down-regulatory immune pathways (including …

… The reasons for exclusion of studies are illustrated in Figure 1 . Thus, a total of eight clinical
trials were considered eligible for the meta-analysis, including one Phase II study and seven …

… Immune check point inhibitors (ICI) have secured regulatory approvals across the world for
the treatment of … of these agents to kidney toxicity has been neglected and underestimated. …

… The aim of this article is to review the diagnosis and management of patients with immune-mediated
colitis, which should be identified early and addressed promptly to avoid detrimental …