… Our findings indicate that the NTS-DBL2X region of VAR2CSA can elicit strain-transcending
anti-adhesion antibodies and suggest that the combination of the two major variants used …

… VAR2CSA comprises an intracytoplasmic region, a … a similar pattern of activity as naturally
acquired antibody needs to … to epitopes from different variants of VAR2CSA. Investigations are …

… the antibody response towards different VAR2CSA variants may … Experimental designs
based on the use of single domain … The NTS-DBL2X region of VAR2CSA induces cross-reactive …

… The protein VAR2CSA, a member of the PfEMP1 variant … dependent acquisition of
VAR2CSA-specific antibody appears to be … Timing of sample collection during pregnancy or …

… naturally acquired antibodies; these patterns differ between … that these atypical migration
patterns could arise from incorrect … the differential binding affinity of various alleles of VAR2CSA …

… by antibodies induced by the full-length VAR2CSA protein [… position of the NTS-DBL2X
protein sequence alignment to … In this new clustering pattern, FCR3- and 3D7-like variants, as …

… of the pattern seen for BIA against the parasite variants (see … might be related to the differential
display of antigens on the IE … to identify VAR2CSA epitopes shared by multiple variants of …

… full-length recombinant VAR2CSA protein able to induce adhesion-inhibitory antibodies
has … the quantity of IgG present in the plasma sample. Ninety-six well plates coated with …

… Mouse antibodies showed similar patterns of reactivity with ICAM-1-binding and nonbinding
isolates, and reacted with a parasite isolate from a different genome (3D7). Surprisingly, we …

… to identify the VAR2CSA domains and variants that could be … in the pattern of inhibition by
the different IgG antibodies … -terminal portion of VAR2CSA (NTS-DBL2X) inhibited the majority …