[HTML][HTML] Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival
… recruit a number of different docking proteins through the … This difference in biological
outcome supports the idea that … 1 mm glutamine, whereas the neuroblastoma cell line SK-N-MC …
outcome supports the idea that … 1 mm glutamine, whereas the neuroblastoma cell line SK-N-MC …
[HTML][HTML] The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation
M Ferro, MT Savino, B Ortensi, F Finetti, L Genovese… - PLoS …, 2011 - journals.plos.org
… Rai/ShcC is a member of the Shc family of protein adaptors … As neuronal progenitors
differentiate ShcA is progressively … different cell types is intriguing but not unique. A similar dual …
differentiate ShcA is progressively … different cell types is intriguing but not unique. A similar dual …
The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications
C Russo, V Venezia, E Repetto, M Nizzari… - Brain Research …, 2005 - Elsevier
… protein Grb2 both in human brain and in neuroblastoma … APP for the induction of different
cellular pathways. This has … ShcC, which is co-precipitated with CTFs in human brain, as …
cellular pathways. This has … ShcC, which is co-precipitated with CTFs in human brain, as …
[HTML][HTML] A review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma
V Mlakar, E Morel, SJ Mlakar, M Ansari… - Journal of Experimental …, 2021 - Springer
… of its deregulation in neuroblastoma, and current promising therapeutics targeting … cell
function as one of the central signaling axes that affect many different cellular functions (…
function as one of the central signaling axes that affect many different cellular functions (…
RAI (ShcC/N-Shc)-dependent recruitment of GAB1 to RET oncoproteins potentiates PI3-K signalling in thyroid tumors
… to several different proteins with similar functions. The CH1 … of neuronal survival and
differentiation, kidney development, … found in a large set of neuroblastoma cell lines. In these cells …
differentiation, kidney development, … found in a large set of neuroblastoma cell lines. In these cells …
[图书][B] Regulation of IGF-1 receptor signaling by autophagy in human neuroblastoma cell lines
M Soori - 2014 - search.proquest.com
… risk neuroblastoma remains high, in some cases the disease displays a strikingly unique …
In one cascade Shc docking proteins are recruited to the activated receptor (not shown) that …
In one cascade Shc docking proteins are recruited to the activated receptor (not shown) that …
The Identification of Novel Binding Partners of the Neuronal Adaptor Protein ShcC
RI Grant - 2009 - ir.lib.uwo.ca
… In Neuroblastoma NB-39-nu cells, a distinct function for the … 2) To differentiate the interaction
profiles of the ShcC PTB and … as docking sites for other proteins, and specifically the ShcC …
profiles of the ShcC PTB and … as docking sites for other proteins, and specifically the ShcC …
RET and neuroendocrine tumors
M Ichihara, Y Murakumo, M Takahashi - Cancer letters, 2004 - Elsevier
… Growth, differentiation and functions of neuroendocrine cells are controlled by a variety of …
turned out to be the binding site of at least five different docking proteins, SHC, FRS2, DOK4/5 (…
turned out to be the binding site of at least five different docking proteins, SHC, FRS2, DOK4/5 (…
[HTML][HTML] Positive association of human SHC3 gene with schizophrenia in a Northeast Chinese Han population
Y Lv, Y Sun, GY Wang, J Yin, CJ Li, YY Luo… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
… transforming protein 3 (SHC3), also known as N-Shc, ShcC … of cancer, including aggressive
neuroblastomas and human … different genetic models, and one of them showed difference …
neuroblastomas and human … different genetic models, and one of them showed difference …
[PDF][PDF] Cathepsin Inhibition Prevents Autophagic Protein Turnover and Down-Regulates IGF-1 Receptor Mediated Signaling in Neuroblastoma
M Soori, G Lu, RW Mason - Journal of Pharmacology and …, 2015 - researchgate.net
… causes cell death in neuroblastoma by dysregulation of cell … Specifically, we examine the
role of cathepsins in regulation … ) Distinct role of ShcC docking protein in the differentiation of …
role of cathepsins in regulation … ) Distinct role of ShcC docking protein in the differentiation of …