Comparative genetic architectures of schizophrenia in East Asian and European populations
…, Genetic REsearch on schizophreniA neTwork-China … - … genetics, 2019 - nature.com
… Common genetic variants that confer risk for schizophrenia … schizophrenia variants to have
different effects in different … signatures converge on the conclusion that the schizophrenia …
different effects in different … signatures converge on the conclusion that the schizophrenia …
Molecular mechanisms of schizophrenia
… In a unifying hypothesis, different cascades merge into another that … with schizophrenia
[87], and carriers of a genetic variation in the dysbindin1 gene have demonstrated a functional …
[87], and carriers of a genetic variation in the dysbindin1 gene have demonstrated a functional …
Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder
… Genetic studies have identified genetic variants that … for schizophrenia genetic research,
and these genes were identified by different kinds of studies including convergent functional …
and these genes were identified by different kinds of studies including convergent functional …
Genetic insights into the neurodevelopmental origins of schizophrenia
R Birnbaum, DR Weinberger - Nature Reviews Neuroscience, 2017 - nature.com
… The diverse and protean effects of genetic and epigenetic … — perhaps thousands of —
genetic variants that are common in … The present article focuses on this emerging convergence, …
genetic variants that are common in … The present article focuses on this emerging convergence, …
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
LM Camargo, V Collura, JC Rain, K Mizuguchi… - Molecular …, 2007 - nature.com
… (DTNBP1), a second schizophrenia risk gene, we show that … that the function of schizophrenia
risk genes may converge. … different genes as well as several fragments for a given gene …
risk genes may converge. … different genes as well as several fragments for a given gene …
Functional gene-expression analysis shows involvement of schizophrenia-relevant pathways in patients with 22q11 deletion syndrome
NJM van Beveren, LC Krab, S Swagemakers… - PLoS …, 2012 - journals.plos.org
… of the genes identified by LAP and of genes with different expression … A recent report has
shown that genetic variation in … points of convergence between genetic and functional genomic …
shown that genetic variation in … points of convergence between genetic and functional genomic …
Human genetic variation and its contribution to complex traits
… our knowledge of the various forms of human genetic variation, their … This convergence of
genes associated with multiple … rare structural variants and autism and schizophrenia have …
genes associated with multiple … rare structural variants and autism and schizophrenia have …
New gene discoveries highlight functional convergence in autism and related neurodevelopmental disorders
… points of convergence among these genes with diverse biological … fold enrichment for rare
inherited variants). This study reported 102 … associated with ASD, NDD, schizophrenia (SCZ), …
inherited variants). This study reported 102 … associated with ASD, NDD, schizophrenia (SCZ), …
A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples
P Roussos, P Katsel, KL Davis, LJ Siever… - Archives of general …, 2012 - jamanetwork.com
… (SZ) that can be derived from studies of genetic variants and … large gene expression microarray
data set in 4 different brain … found the existence of convergent molecular abnormalities in …
data set in 4 different brain … found the existence of convergent molecular abnormalities in …
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
…, Schizophrenia Working Group of the … - … Molecular Genetics, 2019 - academic.oup.com
… , functional characterization of these variants provided the … correlated with schizophrenia,
there is converging evidence that … common genetic variants influencing the risk of 19 different …
there is converging evidence that … common genetic variants influencing the risk of 19 different …