Converging evidence for the association of functional genetic variation in the serotonin receptor 2a gene with prefrontal function and olanzapine treatment

G Blasi, C De Virgilio, A Papazacharias… - JAMA …, 2013 - jamanetwork.com
… The results of the present study converge in suggesting an … phenotypes linked with genetic
risk for schizophrenia. In particular, … relevant to schizophrenia and located at different points …

Adaptive evolution of genes underlying schizophrenia

B Crespi, K Summers, S Dorus - Proceedings of the …, 2007 - royalsocietypublishing.org
convergent evidence consistent with the hypothesis that … signals over different time scales,
and for different types of … on genes implicated in schizophrenia may localize functional sites …

Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay

R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
… on gene expression (epigenetics) and convergence of genes and … with genetic variation in
at least two different ways [46]. … common and rare genetic variants associated with psychotic …

Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia

A Torkamani, B Dean, NJ Schork… - Genome research, 2010 - genome.cshlp.org
Gene network overlaps. Heatmaps displaying the overlap … eight genes from Modules 7, 14,
and 18 related to different … identified a genetic variant (rs1344706) in the ZNF804A gene, a …

Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain

E Radulescu, AE Jaffe, RE Straub, Q Chen… - Molecular …, 2020 - nature.com
different signaling pathways in our co-expression networks … have stressed genes in tier
1 because of the convergence of … some overlap in gene networks between genetic risk and …

Revisiting antipsychotic drug actions through gene networks associated with schizophrenia

K Kauppi, SB Rosenthal, MT Lo… - American Journal of …, 2018 - Am Psychiatric Assoc
… another and converge on related biological and functional networks (… Genetic variations in
CYP2D6, a gene linked to drug … in different brain areas has been linked to different aspects of …

[HTML][HTML] Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

ES Lips, LN Cornelisse, RF Toonen, JL Min… - Molecular …, 2012 - nature.com
… whether genetic variation associated with schizophrenia risk accumulates in functional gene
… As the genetic variants were drawn from different pools, every control method tested slightly …

Genome-wide expression profiling of schizophrenia using a large combined cohort

M Mistry, J Gillis, P Pavlidis - Molecular psychiatry, 2013 - nature.com
… As the genes we identified were functionally diverse, we … of gene networks. In particular, we
asked whether the signature … against gene lists derived from a recent review on convergent

Genetic variability in scaffolding proteins and risk for schizophrenia and autism-spectrum disorders: a systematic review

J Soler, L Fañanás, M Parellada, MO Krebs… - Journal of Psychiatry and …, 2018 - jpn.ca
… show a certain convergence on reporting genes involved in glutamatergic synapse plasticity.…
The nature and function of the different families of scaffolding proteins included in this review…

Gene expression elucidates functional impact of polygenic risk for schizophrenia

M Fromer, P Roussos, SK Sieberts, JS Johnson… - Nature …, 2016 - nature.com
… on gene expression of genetic variants previously implicated in risk; (ii) genes showing a
significant difference … expression analysis display various degrees of cell-type specificity, which …