Genetics of schizophrenia
I Escudero, M Johnstone - Current psychiatry reports, 2014 - Springer
… These candidate genes converge on key neuronal signalling … these variants led to the
establishment of different consortia, … this genetic variant brings about the structural and functional …
establishment of different consortia, … this genetic variant brings about the structural and functional …
What genes are differentially expressed in individuals with schizophrenia? A systematic review
AK Merikangas, M Shelly, A Knighton, N Kotler… - Molecular …, 2022 - nature.com
… Gaining insight into the mechanistic influences of these genetic variants … and rare genetic
variants, as well as diverse environmental … with specific classes of loss-of-function variants [27]. …
variants, as well as diverse environmental … with specific classes of loss-of-function variants [27]. …
Genomics, convergent neuroscience and progress in understanding autism spectrum disorder
… , or intersection, of diverse ASD genetic risks with respect to … for rare damaging variants
(case–control, schizophrenia only)… of ultra-rare genetic variation, the characterization of …
(case–control, schizophrenia only)… of ultra-rare genetic variation, the characterization of …
Cortical cellular diversity and development in schizophrenia
… to conducting cell type-specific functional genomic studies in … risk attributed to common
genetic variation. For instance, an … of schizophrenia to improve and converge at the cellular level. …
genetic variation. For instance, an … of schizophrenia to improve and converge at the cellular level. …
The polygenic architecture of schizophrenia—rethinking pathogenesis and nosology
… , many individuals with schizophrenia endure poor societal functioning, stigma and a poor
… and rare genetic variants that implicate various biological pathways in schizophrenia. We …
… and rare genetic variants that implicate various biological pathways in schizophrenia. We …
Copy number variation in schizophrenia in Sweden
JP Szatkiewicz, C O'Dushlaine, G Chen… - Molecular …, 2014 - nature.com
… of genes intersected by rare CNVs implicated functional … This convergence from different
methodologies minimizes risk … We hypothesized that different types of genetic variation can …
methodologies minimizes risk … We hypothesized that different types of genetic variation can …
Genes and environments in schizophrenia: the different pieces of a manifold puzzle
JM Réthelyi, J Benkovits, I Bitter - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
… how the different forms of genetic variation interact and how … is how genetic and
environmental effects converge on … genetic variability at a specific functional polymorphism of a …
environmental effects converge on … genetic variability at a specific functional polymorphism of a …
Rethinking the first episode of schizophrenia: identifying convergent mechanisms during development and moving toward prediction
JK Forsyth, CE Bearden - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
… which genetic variants associated with schizophrenia increase risk… to maximize psychosis
prediction under different contexts. … and functional brain changes in first episode psychosis and …
prediction under different contexts. … and functional brain changes in first episode psychosis and …
The genomics of schizophrenia: update and implications
P Giusti-Rodríguez, PF Sullivan - The Journal of clinical …, 2013 - Am Soc Clin Investig
… and genetic epidemiological studies have converged on the … data, the genetic architecture
of schizophrenia is diverse and … the genetic variants that increase risk for schizophrenia differ …
of schizophrenia is diverse and … the genetic variants that increase risk for schizophrenia differ …
Evaluating historical candidate genes for schizophrenia
… , we assumed that genetic variants act on the gene it was in … converging on the null. This is
important because the candidate … Best practices in 2014 are thus very different from 2004. For …
important because the candidate … Best practices in 2014 are thus very different from 2004. For …