… can result in tear film inadequacy. In … of orally administered doxycycline in rabbits after a
chemical burn and their findings suggest that the dose of 5 mg/kg once a day of doxycycline can …

… Oral tetracyclines are commonly used to treat DED given their dual impact of broad spectrum
antibacterial prophylaxis (though only minocycline and doxycycline are able to reach an …

… TBUT and meibomian gland expression compared to systemic doxycycline (Group B) (p<…
to systemic doxycycline. The localized action and superior outcomes in tear film stability and …

… RCES with oral doxycycline in our series had a much lower efficacy than what is reported
in … Does orally administered doxycycline reach the tear film? Br J Ophthalmol. 2008;92(6):856-…

… on the amount of orally administered doxycycline that can reach the eye surface. For …
which were given oral doxycycline, the drug was easily found in the blood but the tear film was …

… For instance, oral doxycycline can be used as adjunctive … in tear fluid of dogs following
oral administration at doses … The present study describes, for the first time, the tear film PK of …

… had significantly higher tear film MMP-… oral doxycycline were found to have significantly
decreased collagenase activity in an alkali-burn cornea model.Topical methylprednisolone given …

… secretions may be due to dysfunction or destruction of the lacrimal gland or a scarring/blockage
of the lacrimal gland ductules, which prohibits the aqueous secretions from reaching the …

… ingestion of chelators, oral administration … Doxycycline is unique in that it is excreted primarily
in the feces and thus … gland orifices, unstable tear film, and inferior superficial …