Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme
… it is an important indication of disease relapse, graft rejection … reflect the risk of relapse in
chronic myeloid leukemia (CML). … of the donor's cells in order to assess the chimerism status (…
chronic myeloid leukemia (CML). … of the donor's cells in order to assess the chimerism status (…
Monitoring of lineage-specific chimaerism allows early prediction of response following donor lymphocyte infusions for relapsed chronic myeloid leukaemia
N Gardiner, M Lawler, JM O'Riordan… - … marrow transplantation, 1998 - nature.com
… The aims of this study were (1) to measure the degree of donor chimaerism and its relevance
prior to DLI; (2) to monitor changes in the chimaeric profile during the pancytopenic phase …
prior to DLI; (2) to monitor changes in the chimaeric profile during the pancytopenic phase …
[HTML][HTML] Mixed T lymphocyte chimerism after allogeneic hematopoietic transplantation is predictive for relapse of acute myeloid leukemia and myelodysplastic …
HC Lee, RM Saliba, G Rondon, J Chen… - … Marrow Transplantation, 2015 - Elsevier
… complete donor myeloid chimerism by post-transplantation day +… lymphocyte chimerism on
disease progression. T lymphocyte … chimerism was a stronger predictor of relapse and overall …
disease progression. T lymphocyte … chimerism was a stronger predictor of relapse and overall …
Role of minimal residual disease and chimerism after reduced-intensity and myeloablative allo-transplantation in acute myeloid leukemia and high-risk …
T Bernal, M Diez-Campelo, V Godoy, S Rojas… - Leukemia Research, 2014 - Elsevier
… best predictor of relapse after SCT in patients with aggressive … cells) or full chimerism (more
than 95% donor cells). Samples … For event free survival, the event analyzed was relapse or …
than 95% donor cells). Samples … For event free survival, the event analyzed was relapse or …
[HTML][HTML] Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia
B Wiedemann, E Klyuchnikov, N Kröger… - Experimental …, 2010 - Elsevier
… alleles had better 2-year disease-free survival (85%) than … acute leukemias or chronic
myeloid malignancies 27, 28, 29. … the minimum percentages of donor chimerism in this period. …
myeloid malignancies 27, 28, 29. … the minimum percentages of donor chimerism in this period. …
[HTML][HTML] Increasing chimerism after allogeneic stem cell transplantation is associated with longer survival time
X Tang, G Alatrash, J Ning, H Jakher, P Stafford… - … Marrow Transplantation, 2014 - Elsevier
… Assessing a possible association between chimerism and disease-free survival (… Relapse
of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor …
of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor …
[HTML][HTML] Allogeneic hematopoietic cell transplantation in multiple myeloma: focus on longitudinal assessment of donor chimerism, extramedullary disease, and high …
… the impact of several other disease- and treatment-related … was associated with shorter
progression-free survival (PFS) (… the post-transplantation period is the analysis of the donor …
progression-free survival (PFS) (… the post-transplantation period is the analysis of the donor …
Very early lineage-specific chimerism after reduced intensity stem cell transplantation is highly predictive of clinical outcome for patients with myeloid disease
FAM Kinsella, CF Inman, A Gudger, YT Chan… - Leukemia research, 2019 - Elsevier
… and T-cell donor chimerism 50 days after transplantation and … risk of disease relapse and
a reduction in relapse-free survival [8]. … predictor of full donor status at day 50. Recipient/…
a reduction in relapse-free survival [8]. … predictor of full donor status at day 50. Recipient/…
… graft‐versus‐host‐disease‐free event‐free survival in Fanconi anaemia patients undergoing matched related‐ and unrelated‐donor bone marrow transplantation …
F Bernard, CRS Uppugunduri, S Meyer… - British Journal of …, 2021 - Wiley Online Library
… malignancies, especially acute myeloid leukaemia (AML) and … neutrophil recovery with
donor chimaerism was achieved … an indication to transplant but no available matched donor. …
donor chimaerism was achieved … an indication to transplant but no available matched donor. …
… pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation
RL Truitt, AA Atasoylu - 1991 - ashpublications.org
… than 80% of donor origin in mice tested 70 to 150 days post-… Body weight loss can be a
sensitive indicator of GVHD." … , the probability of relapse, survival, and disease-free survival is …
sensitive indicator of GVHD." … , the probability of relapse, survival, and disease-free survival is …