The orofacial formalin test in rats: effects of different formalin concentrations

P Clavelou, R Dallel, T Orliaguet, A Woda… - Pain, 1995 - journals.lww.com
was delayed until 15 min (block 6) and remained significantly … lowest formalin concentrations
(0.2%), the oedema was not … and Cowan, A., Naloxone causes apparent antinociception

Implication of allopregnanolone in the antinociceptive effect ofN-palmitoylethanolamide in acute or persistent pain

O Sasso, R Russo, S Vitiello, GM Raso, G D'agostino… - Pain, 2012 - journals.lww.com
… of acute and persistent pain, the formalin test and carrageenan-induced paw edema. The
pivotal … significant at the highest doses (5 and 50μg/paw) at different early and delayed interval …

Ulinastatin exhibits antinociception in rat models of acute somatic and visceral pain through inhibiting the local and central inflammation

MX Zhan, L Tang, YF Lu, HH Wu, ZB Guo… - Journal of Pain …, 2021 - Taylor & Francis
… Moreover, ip administration of ulinastatin was also able to delay the occurrence of … Display
full size … ulinastatin could also persistently inhibit formalin-induced paw edema and ulcer …

Antiinflammatory and antinociceptive activities of Blechnum occidentale L. extract

FR Nonato, TAA Barros, AM Lucchese… - Journal of …, 2009 - Elsevier
… of formalin, we suggest that its antinociceptive activity is due, … was able to effectively inhibit
the oedema in both the earlier and … This delayed antiinflammatory effect could indicate that it is

[HTML][HTML] Preemptive analgesia: moving beyond conventional strategies and confusing terminology

BK Taylor, TJ Brennan - The Journal of Pain, 2000 - Elsevier
antinociception studies have shown preinjury versus postinjury effects of peripherally applied
local anesthetics. In the formalin test… plexus block might delay the time to first analgesic …

[PDF][PDF] Anti-inflammatory and analgesic activities of Artemisia absinthium and chemical composition of its essential oil

A Hadi, N Hossein, P Shirin, N Najmeh… - Int J Pharm Sci Rev …, 2014 - researchgate.net
… AEAA in early and late phases of the formalin test are shown … Therefore, antinociceptive
activity of drugs may be related to … delayed edema is sustained by prostaglandin release and is

The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors

KP Zeitz, N Guy, AB Malmberg, S Dirajlal… - Journal of …, 2002 - Soc Neuroscience
… The second phase results in part from a delayed inflammatory … , we assessed the magnitude
of swelling produced by … 3 R is not involved in the antinociceptive effect of serotonin. …

[HTML][HTML] Antinociceptive activities and the mechanisms of anti-inflammation of asiatic acid in mice

SS Huang, CS Chiu, HJ Chen, WC Hou… - … Complementary and …, 2011 - hindawi.com
formalin-induced pain in the late phase. In the anti-inflammatory test, AA decreased the paw
edema … The first phase peaks at 3h, and the delayed phase peaks at 48h after Carr injection. …

Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia

AH Lichtman, CC Shelton, T Advani, BF Cravatt - Pain, 2004 - Elsevier
… of the formalin test accompanied with a phenotypic anti-edema … displayed a phenotypic
anti-nociception compared to wild … phasic component and a delayed tonic nociceptive response …

Analgesic and anti-inflammatory effects of the methanol root extracts of some selected Nigerian medicinal plants

IO Ishola, EO Agbaje, OO Adeyemi… - Pharmaceutical …, 2014 - Taylor & Francis
… analgesia, as shown by the delays in reaction time with a peak … the central and the peripheral
antinociceptive action. … the carrageenan-induced paw edema model where the extracts …