4-Phenylselenyl-7-chloroquinoline, a new quinoline derivative containing selenium, has potential antinociceptive and anti-inflammatory actions

M Pinz, AS Reis, V Duarte, MJ da Rocha… - European journal of …, 2016 - Elsevier
… The DCF fluorescence intensity emission was recorded at 520 nm … PSQ potentially reduced
the nociceptive behavior in the first (… in reducing the paw edema formation in the formalin test. …

Anti-inflammatory and antinociceptive effects, and safety toxicological profile of a new paracetamol analog, LQFM291

LC Turones, LS Machado, BG Vaz… - …, 2023 - Springer
… paracetamol showed a similar antinociceptive effect in formalin test compared to LQFM291.
… and edema tests were performed, paracetamol showed a delayed antinociceptive and anti-…

Antinociceptive effect of butyl (2-phenylethynyl) selenide on formalin test in mice: evidences for the involvement of serotonergic and adenosinergic systems

C Luchese, M Prigol, CI Acker, CW Nogueira - European journal of …, 2010 - Elsevier
… of oedema formation, we measured the paw oedema by … , for the first time, the antinociceptive
effect produced by butyl … with atropine did not prevent the antinociceptive effect of butyl (2-…

The antinociceptive effect of adalimumab, a TNF-alpha inhibitor, in a mice model of inflammatory pain

M Öz, H Şimşek - Türk Doğa ve Fen Dergisi, 2020 - dergipark.org.tr
… pulmonary edema and histological damage due to … This test is based on recording the
delay in the experimental … adalimumab has an antinociceptive effect in the formalin test. …

[HTML][HTML] … of Cajanus cajan (L) Millsp. produced antinociceptive and anti-inflammatory actions through inhibition of inflammatory mediators and activation of opioidergic …

TG Olubodun-Obadun, IO Ishola, CA Osumuo… - Phytomedicine Plus, 2023 - Elsevier
… the early and late phases of formalin-induced inflammatory pain… , we did not observe any
sign of toxic behaviour nor delayed … In this study, the oedema formation was maximal at 5 h after …

Control of pain initiation by endogenous cannabinoids

A Calignano, GL Rana, A Giuffrida, D Piomelli - Nature, 1998 - nature.com
… To test this possibility, we measured the antinociceptive … of PEA were not accompanied by
a reduction in inflammatory oedema (… Time delays to escape jumping or hind-paw licking were …

Primary afferent tachykinins are required to experience moderate to intense pain

YQ Cao, PW Mantyh, EJ Carlson, AM Gillespie… - Nature, 1998 - nature.com
… , and one that is secondary to a delayed inflammatory response (… The magnitude of pain
behaviour produced by oedema … Because of the inconsistency in the antinociceptive effects of NK…

Behavioral and immunohistochemical evidence for central antinociceptive activity of botulinum toxin A

I Matak, L Bach-Rojecky, B Filipović, Z Lacković - Neuroscience, 2011 - Elsevier
… BTX-A reduce phase II of formalin-induced pain. … reduction of edema in inflamed paw tissue.
The most logical explanation … However, in the present experiment this action was delayed, …

The water-soluble fraction of bee venom produces antinociceptive and anti-inflammatory effects on rheumatoid arthritis in rats

YB Kwon, HJ Lee, HJ Han, WC Mar, SK Kang… - Life sciences, 2002 - Elsevier
… The intensity of the light source was calibrated to produce … in RA-BAE group was delayed,
being first evident at 21 days … present study with both paw edema and radiological analysis. …

Neo-clerodane diterpenic influence in the antinociceptive and anti-inflammatory properties of Salvia circinnata Cav.

MP Fernando, HL Alberto, VDM Guadalupe… - Journal of …, 2021 - Elsevier
… using the plantar test and carrageenan-induced edema. The … was a beam emitted by a
caloric source with an intensity of … treatments in the formalin test in contrast to a delay of almost …