Riluzole combination therapy for moderate-to-severe major depressive disorder: a randomized, double-blind, placebo-controlled trial

E Salardini, A Zeinoddini, P Mohammadinejad… - … of psychiatric research, 2016 - Elsevier
… Resistant patients are usually managed by switching treatment … this is the first randomized
placebo-controlled trial which … similar efficacy to conventional antidepressants. Response and …

Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study

MC Rowbotham, V Goli, NR Kunz, D Lei - Pain, 2004 - Elsevier
… effective than SSRI antidepressants for chronic pain, but may … before the first dose of
double-blind study medication served … mean change from baseline in VAS-PI scores in patients

A randomized, double-blind, placebo-controlled, 8-week study of vilazodone, a serotonergic agent for the treatment of major depressive disorder

A Khan, AJ Cutler, DK Kajdasz, S Gallipoli… - The Journal of clinical …, 2011 - psychiatrist.com
… vilazodone with placebo, using change from baseline to end … , patients were required to
discontinue any antidepressant or … and the mean age at first occurrence of MDD was 32.6 years. …

Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial

S Akhondzadeh, L Kashani, A Fotouhi… - Progress in Neuro …, 2003 - Elsevier
… , 4th edition, for major depression based on the structured … contrast was performed in the
change from baseline for HAM-D … was carried out to investigate the possible antidepressant

A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression

KD Wagner, J Jonas, RL Findling, D Ventura… - Journal of the American …, 2006 - Elsevier
Patients (6-17 years old) with major depressive disorder … The primary efficacy measure
was the mean change from … (SSRIs) are considered first-line antidepressant treatment for …

Intrathecal ziconotide in the treatment of chronic nonmalignant pain: a randomized, doubleblind, placebo‐controlled clinical trial

, … Nonmalignant Pain Study 96‐002 Group - … : Technology at the …, 2006 - Wiley Online Library
… , opioids were used by 75% of patients, antidepressants by 59%, … 166 (15.7%) patients going
from normal at baseline to above the … that Robert Presley, MD, made to this study and to the …

Bright light in elderly subjects with nonseasonal major depressive disorder: a double blind randomised clinical trial using early morning bright blue light comparing …

R Lieverse, MMA Nielen, DJ Veltman, BMJ Uitdehaag… - Trials, 2008 - Springer
… , circadian phase shifting, and antidepressant effects [33, 34]. … as an adjuvant to conventional
antidepressants. Therefore, … subscales have earlier been shown to be moderately reliable …

Restless legs syndrome improved by pramipexole: a double-blind randomized trial

J Montplaisir, A Nicolas, R Denesle… - Neurology, 1999 - AAN Enterprises
… However, this change is small compared with the treatment … has also produced an
antidepressant effect.34 Therefore, it … several patients reported mild nausea during the first few …

[HTML][HTML] … , placebo‐controlled pilot study of the phosphodiesterase‐3 inhibitor cilostazol as an adjunctive to antidepressants in patients with major depressive disorder

MS Abdallah, AN Ramadan… - CNS neuroscience & …, 2021 - ncbi.nlm.nih.gov
… , this study is the first doubleblind, randomized, and placebo‐… restored to the normal levels
by the antidepressant therapy. … a decrease in HDRS after switching from milnacipran to CLS (…

… , and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life: a randomised, double-blind, placebo-controlled trial

EJ Lenze, BH Mulsant, DM Blumberger, JF Karp… - The Lancet, 2015 - thelancet.com
antidepressant trial before enrolling in this study. By … major depressive disorder and this
extent of treatment resistance remit when given augmentation treatment in randomised trials