… of change during the study P < .… study was not a controlled, randomized trial and the
medications were stable for 3 to 4 weeks; therefore, it was possible that the delayed antidepressant …

… period, while patients randomized to placebo were switched … of MDD within the first 24 weeks
of the double-blind period. … open-label antidepressant treatment of MDD followed by a six-…

… For the first week of double-blind therapy all patients in the … of patients with severe depression
on the change from base… was a superior antidepressant to placebo in outpatients with …

… pain in patients with MDD, and overall QOL also improved. In a … of the study indicated that
optimized antidepressant therapy, … discontinued or switched from their initial antidepressant by …

… from 4 double-blind, placebo-controlled, randomized trials of … direct effect on pain improvement
and change in mood … mood and pain, and how the analgesic and antidepressant effects …

… a computerized random number generator, we randomized study … of any change from baseline
to endpoint in HAM-D total score. … , our study is the first adequately powered randomized, …

… has demonstrated both antidepressant and analgesic efficacy … these studies in this
meta-analysis was its first submission … The effect sizes for change in pain and depression scales …

… the change in the Brief Pain Inventory (BPI) average pain score … of major depressive disorder,
diabetic neuropathic pain, and … analgesic activity independent of its antidepressant effect. …

… and change of medication are highly recommended. … , several studies indicate that the
efficacy of antidepressants is … , to our knowledge, Ghanizadeh and Hedayati (2013) were the first …

… could be to test antidepressants in first-ever depressive … in a sample of MDD Cuban outpatients
previously naive to SSRIs, an … , and patients switched to tricyclic antidepressants if they …