CYP3A activity based on plasma 4β-hydroxycholesterol during the early postpartum period has an effect on the plasma disposition of amlodipine
T Naito, N Kubono, T Ishida, S Deguchi… - … and Pharmacokinetics, 2015 - Elsevier
… sourced from 10 healthy non-perinatal women were obtained from Kohjin … pharmacokinetics
of amlodipine were reported to be affected by the haplotypes of the ABCB1 gene in humans […
of amlodipine were reported to be affected by the haplotypes of the ABCB1 gene in humans […
… coupled to LC-MS/MS for simultaneous determination of amlodipine, olmesartan and hydrochlorothiazide in plasma samples: Application to pharmacokinetic studies
… Drug-free K 3 EDTA human plasma samples were harvested on-site from healthy volunteers…
Similarly the deduced pharmacokinetic parameters of HCT came in close agreement with …
Similarly the deduced pharmacokinetic parameters of HCT came in close agreement with …
ABCG2 Single Nucleotide Polymorphism Affects Imatinib Pharmacokinetics in Lower Alpha-1-Acid Glycoprotein Levels in Humans
… pharmacokinetics in a controlled study of healthy subjects. We hypothesized that the effect of
ABCG2 and ABCB1 … the ABCG2 and ABCB1 genotypes, a blood sample was obtained from …
ABCG2 and ABCB1 … the ABCG2 and ABCB1 genotypes, a blood sample was obtained from …
ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence
… There is some inter-individual variation in the pharmacokinetics of … A difference in the ABCB1
haplotype profile was found between … Blood samples were obtained and genomic DNA was …
haplotype profile was found between … Blood samples were obtained and genomic DNA was …
Effect of multi-drug resistance gene-1 C3435T genetic polymorphism on the concentration of cyclosporine a pharmacokinetics: a meta-analysis
H Li, W Ping, L Song, C Guo, W Zheng - Chinese Journal of Tissue …, 2012 - cjter.com
… Amlodipine,but not MDR1 polymorphisms,alters the … The MDR1/ABCB1 gene,a high-impact
risk factor for cardiac … and CYP3A4 genes in Asians and the influence of MDR1 haplotypes …
risk factor for cardiac … and CYP3A4 genes in Asians and the influence of MDR1 haplotypes …
[图书][B] The Effect of Genetic Polymorphism in MDR1 Gene on Cyclosporine Blood Concentration in Jordanian Renal Transplant Patients
EKR Al-Manassrah, N Bulativa, AM Yousef - 2008 - platform.almanhal.com
… -drug resistance-1 (MDR1), also known as the (ABCB1 gene or ATP … between individuals
who received calcium channel blockers (… on cyclosporine pharmacokinetics in 16 patients who …
who received calcium channel blockers (… on cyclosporine pharmacokinetics in 16 patients who …
[图书][B] Pharmacodynamic effects of xenobiotic ABC transporters in peripheral tissues
LW Chinn - 2008 - search.proquest.com
… drug plasma levels in healthy subjects. Researchers have also … no effect of ABCB1 SNPs
on digoxin pharmacokinetics [156, … that transplant patients with the 3435T allele or haplotypes …
on digoxin pharmacokinetics [156, … that transplant patients with the 3435T allele or haplotypes …
The drug transporter ABCB1 c.3435C>T SNP influences artemether–lumefantrine treatment outcome
… membrane of the hepatocyte, the ABCB1 (MDR1/Pgp) ATP-binding … hypothesized that small
pharmacokinetic differences might … and a capillary blood sample obtained for PCR analysis. …
pharmacokinetic differences might … and a capillary blood sample obtained for PCR analysis. …
Identification of genetic variants associated with response to statin therapy
JL Mega, DA Morrow, A Brown… - … , and vascular biology, 2009 - Am Heart Assoc
… of the APOE ε2 haplotype versus ε4 haplotype had significantly … genes involved in statin
pharmacokinetics: ABCB1, CYP3A4, … -analysis of healthy subjects where ε2/ε2 individuals had 30…
pharmacokinetics: ABCB1, CYP3A4, … -analysis of healthy subjects where ε2/ε2 individuals had 30…
Bioequivalence evaluation of two amlodipine salts, besylate and orotate, each in a fixed-dose combination with olmesartan in healthy subjects
SY Lee, JR Kim, JA Jung, W Huh… - Drug design …, 2015 - Taylor & Francis
… Our results were obtained in conditions that may not be relevant to the … Effect of ABCB1
(MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine …
(MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine …