Platelets and atherothrombosis: causes, targets and treatments for thrombosis

TI Siddiqui, DK Dikshit - Current medicinal chemistry, 2013 - ingentaconnect.com
… The present review aims to describe the haemostasis … One of the most important adhesion
molecules bound by GPIIb/IIIa … blood flow in combination with fibrinolytic agents [102103]. …

Platelets: pleiotropic roles in atherogenesis and atherothrombosis

MD Linden, DE Jackson - The international journal of biochemistry & cell …, 2010 - Elsevier
… for blood clots after plaque rupture, leading to ischaemic heart disease. … adhesion molecules,
chemokines, coagulation and fibrinolysis proteins, growth factors, immunologic molecules

Role of inflammation and hypercoagulability in thrombosis

PA Gurbel, N Apte, US Tantry - … in cardiovascular disease, 2014 - Wiley Online Library
adhesion molecules such as intracellular cell adhesion … complications by attenuating
fibrinolysis. PAI-1 is released from … platelet reactivity, hypercoagulability, coagulation factors, and …

[HTML][HTML] A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C‐reactive protein following myocardial infarction: the CADET …

M Woodward, GDO Lowe, LMA Francis… - … and Haemostasis, 2004 - Elsevier
coronary heart disease … [5], and of fibrinolytic therapy in evolving acute myocardial infarction
(MI) [4]. … , but not cytokines or cellular adhesion molecules. Comparative studies of the …

[HTML][HTML] Endothelial dysfunction, inflammation and coronary artery disease: potential biomarkers and promising therapeutical approaches

DJ Medina-Leyte, O Zepeda-García… - … journal of molecular …, 2021 - mdpi.com
… The canonical role of the hemostatic and fibrinolytic systems … the expression of adhesion
molecules in endothelial cells … ) as compared to clopidogrel and aspirin combined therapy [211]. …

Platelets and antiplatelet therapy in patients with coronary artery disease and diabetes

S Neergaard-Petersen, AM Hvas… - … and hemostasis, 2016 - thieme-connect.com
… prasugrel reduced cardiovascular events more than clopidogrel without a … failure, and
hypertension but also relates to endothelial dysfunction, changes in coagulation and fibrinolysis

Atherothrombosis: a widespread disease with unpredictable and life-threatening consequences

JF Viles-Gonzalez, V Fuster… - European heart …, 2004 - academic.oup.com
… cytokines, express adhesion molecules such as ICAM-1, … The endothelium affects
vascular homeostasis by regulating … ) was comparable to the effect of a fibrinolytic agent (streptokinase)…

[HTML][HTML] Newer antithrombotic drugs

P Sikka, VK Bindra - Indian journal of critical care medicine: peer …, 2010 - ncbi.nlm.nih.gov
… Alpha granules express adhesion molecule P selectin on … factor initiates coagulation (extrinsic
coagulation pathway). … administration, all anticoagulant, antiplatelet, and fibrinolytic

Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms

SP Jackson, R Darbousset… - Blood, The Journal of …, 2019 - ashpublications.org
… -adhesion molecules. They also undermine the natural anticoagulant and fibrinolytic system
on … components of the coagulation, complement, and fibrinolytic cascades and through …

[HTML][HTML] Novel Aspects Targeting Platelets in Atherosclerotic Cardiovascular Disease—A Translational Perspective

A Huseynov, J Reinhardt, L Chandra… - … Journal of Molecular …, 2023 - mdpi.com
… ) and inflammatory mediators, coagulation proteins as well as … cells express important
adhesion molecules on the surface … atherosclerotic disease, such as the activation of fibrinolysis