Defining foci of cellular alteration in short-term and medium-term rat liver tumor models

JA Popp, TL Goldsworthy - Toxicologic Pathology, 1989 - journals.sagepub.com
… a developmental stage in rat liver tumor for… promoting effect of phenobarbital and the
pcroxisome proliferator WY- 14,643 on the size and number of hepatic foci following DEN initiation

Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis

SE Chuang, ML Kuo, CH Hsu, CR Chen, JK Lin… - …, 2000 - academic.oup.com
… The anti-initiation effect may result from its ability to inhibit … the strong tumor promotion
effect of TPA is mediated through … preneoplastic focus formation in rats, shedding light on the …

Cellular biochemistry of the stepwise development of cancer with chemicals: GHA Clowes memorial lecture

E Farber - Cancer Research, 1984 - AACR
… of liver cancer in rats by these dietary deficiencies offers … The effects of several known
promoting agents for the liver … Failureto discriminate initiation from promotion of liver tumors in a …

Comparative developmental and phenotypic properties of altered hepatocyte foci and hepatic tumors in rats

C Peraino, BA Carnes, FJ Stevens, EF Staffeldt… - Cancer research, 1988 - AACR
… of initiation, and (/>)initiation engenders pleiotropic effects on … DEN-initiated he patic lesions,
consisting of hepatic tumors and … diethylnitrosamine administration and promotion with phé…

… , 2-acetylaminofluorene and partial hepatectomy in the expression of glutathione-S-transferase-P and gamma-glutamyltranspeptidase in the early steps of rat liver …

M Ould Elhkim, F Decloître, M Martin, B Loridon-Rosa… - Tumor biology, 1992 - karger.com
… would be able to promote the growth of GST-P-positive cells initiated by DEN, … : Effect of rat
developmental stage at initiation on the expression of biochemical mark ers during liver tumor

The effect of short-term fasting, phenobarbital and refeeding on apoptotic loss, cell replication and gene expression in rat liver during the promotion stage.

H Hikita, EF Nuwaysir, J Vaughan, K Babcock… - …, 1998 - academic.oup.com
initiated cells (19) and to enhance promotion effects (18), such as compensatory cell proliferation
(21,22), in the early stagesgrowth of AHF (58), an enhancing effect on tumor promotion

Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR

R Nishiwaki-Matsushima, T Ohta, S Nishiwaki… - Journal of cancer …, 1992 - Springer
… has a tumor-promoting activity in rat liver, only a few foci were observed in non-initiated rats.
It … The mechanism of action of microcystin in liver cells is similar to that of okadaic acid, and …

Tea antioxidants in cancer chemoprevention

SK Katiyar, H Mukhtar - Journal of Cellular Biochemistry, 1997 - Wiley Online Library
… against tumor initiation, promotion, and progression stages of … effect of tea catechins,
black tea extract, and oolong tea extract on the development of hepatocarcinogenesis in rat

Quantitative Evaluation of the Promotion by 2,3,7,8-Tetrachlorodibenzo-p-dioxin of Hepatocarcinogenesis from Diethylnitrosamine

HC Pitot, T Goldsworthy, HA Campbell, A Poland - Cancer Research, 1980 - AACR
… the promoting effect of TCDD on this 2-stage model of liver … that the promoting action of TCDD
enhances the growth of the cells … The rats in the present study, initiated with DEN and then …

[HTML][HTML] Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action

MA Belury - The Journal of nutrition, 2002 - Elsevier
… the stages of carcinogenesis known as initiation, promotion and … tumor models, dietary
CLA reduced the growth rates of … In terminal end buds of rat mammary tissue initiated with …