… To reconcile these opposing observations, we propose that SR 33589 and amiodarone …
Effects of amiodarone on 5'-deiodination of thyroxine to tri-iodothyronine in rat myocardium. …

… We show that AM reverses T3 or PS4 potentiation of the TSH response to TRH; this effect is
specific … the effect of AM and DEA on basal and TRH-induced TSH release from rat perifused …

… Selenium (Se) status has a modest impact on DIO … rT3 and T4 as well as the 5-deiodination
of ITH sulfates such as T3… to PTU in cerebral cortex of hypothyroid rats, the distinct reaction …

… T4 5'- and 5deiodination in normal and various pathophysiological … specimens of various
tissues of the rat. However, in man, T4 … metabolism of thyroxine. The percentages of T4 5'- and …

… AM decreases the 5′-deiodination of T 4 into T 3 in the liver … /kg·d) for 4 wk had myocardial
concentrations of 28 μmol/kg AM and … One of the side-effects of amiodarone is an increase in …

… and the release of thyroxine and triiodothyronine into the blood;(6) … function of this
isozyme, D1 also catalyzes 5-deiodination. … In areas of iodine sufficiency, amiodarone-induced …

… that D2 and TSH are coexpressed in rat pituitary thyrotrophs … by both triiodothyronine and
thyroxine. Endocrinology 130: … : The effects of amiodarone on serum thyroid hormones and …

… Tri-iodothyronine (T3) is the most active form of thyroid hormone, derived from the deiodination
of the more … T3 is considered to have prominent haemodynamic and metabolic effects. …

… Effects of amiodarone on 5'-deiodination of thyroxine to tri-iodothyronine in rat myocardium.
… RNAs in the rat myocardium by amiodarone and by thyroid status. Clin Sci. 1989;76:463-7. …

… failure or after surgery or myocardial infarction. Some drugs also … In our own longterm study
of the effects of amiodarone, … TSH are seen commonly in subjects treated with amiodarone, …