… these effects result from increased rates of 5′-deiodination. … in patients with severe
amiodarone-induced thyrotoxicosis. … and the putative thyroxine-binding protein p29, in rat brain, …

… that D2 and TSH are coexpressed in rat pituitary thyrotrophs … by both triiodothyronine and
thyroxine. Endocrinology 130: … : The effects of amiodarone on serum thyroid hormones and …

… thyroid hormone metabolism [187], while amiodarone, an anti-… in serum thyroid
hormone levels after myocardial infarction. … a rat liver enzyme converting thyroxine into tri-iodothyronine …

… and the release of thyroxine and triiodothyronine into the blood;(6) … function of this
isozyme, D1 also catalyzes 5-deiodination. … In areas of iodine sufficiency, amiodarone-induced …

… failure or after surgery or myocardial infarction. Some drugs also … In our own longterm study
of the effects of amiodarone, … TSH are seen commonly in subjects treated with amiodarone, …

… D1 catalyses both 5′ and 5 deiodination of T4 to form T3 and … D1 are rT3 (5′ deiodination)
and T3SO4 (5 deiodination). D1 … Hence thyroid hormones have an impact on cardiovascular …

… radioligand assay in rat ventricular myocytes that amiodarone inhibited the … Serum and
myocardial tissue amiodarone concentrations in rabbits that … 4 Amiodarone and thyroid hormones …

… cholecystographic agents) and amiodarone, that decreased hepatic … that the 5'- deiodination
and 5deiodination were accomplished … for in vivo thyroxine 5'- deiodination in the rat. J. Clin. …

… Tri-iodothyronine (T3) is the most active form of thyroid hormone, derived from the deiodination
of the more … T3 is considered to have prominent haemodynamic and metabolic effects. …

… of pituitary TSH secretion after cold exposure of the rats 12,13 … of the inner ring of T4 (5-deiodination)
42 explains the temporal … Amiodarone may reduce the entry of thyroid hormone into …