… by 5′-deiodination to the active form of thyroid hormone T 3 , … The strength of
myocardial contraction depends on several key … The isoform-specific expression of the tri-iodothyronine …

… A decrease in serum T3 implies decreased 5′-deiodination and, in … accompanies high-dose
amiodarone therapy should not be … on the myocardium by the synergism between T3 and …

… of pituitary TSH secretion after cold exposure of the rats 12,13 … of the inner ring of T4 (5-deiodination)
42 explains the temporal … Amiodarone may reduce the entry of thyroid hormone into …

… these effects result from increased rates of 5′-deiodination. … in patients with severe
amiodarone-induced thyrotoxicosis. … and the putative thyroxine-binding protein p29, in rat brain, …

… tri-iodothyronine (T3). The major pathway for the production of circulating T3 is via 5′
deiodination … cardiomyopathy” defines myocardial damage caused by the toxic effects of abundant …

… Some flavonoids such as flavones and aurones feature 5′-deiodination inhibiting properties
at in vitro studies on rat hepatocytes, whereas the homodimeric integral membrane protein …

… Ceppi JA, Zaninovich AA (1989) Effects of amiodarone on 5’-deiodination of thyroxine to
tri-iodothyronine in rat myocardium. J Endocrinol 121: 431-434. Chan HM, Cherian MG (1992) …

… This study reevaluates the relation between thyroid hormone … serve as markers for myocardial
remodeling and apoptosis. … metabolite and suggested product of 5′-deiodination of T 3 , …

… Failure of a patient treated with amiodarone to develop … free thyroxine index and usefulness
of reverse triiodothyronine measurement … 5'-deiodination in rat pituitary that differ in kinetics, …

… of thyroxineand 10 nmol of triiodothyronine each day. Tri-… tissue and is active only in 5'
deiodination. Type III deiodinase is … in patients treated with amiodarone or iodinated radiocontrast …