[PDF][PDF] Effects of estradiol and progesterone on gonadotropin LHβ-and FSHβ-subunit promoter activities in gonadotroph LβT2 cells

H Kanasaki, IN Purwana, T Mijiddorj, U Sukhbaatar… - Neuroendocrinol …, 2012 - nel.edu
gonadotroph cell line, LβT2 cells were used in this study. Cells were transfected with LHβ-
or FSHβ-subunit promoter region-linked luciferase vector, and stimulated with gonadotropin

Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone β-subunit gene expression at the level of the gonadotrope

VG Thackray, SM McGillivray… - Molecular …, 2006 - academic.oup.com
… mRNA levels in ovariectomized rats treated with estrogen and progestin (34) or on LHβ
whether estrogen can modulate transcription of FSHβ-subunit gene expression, the LβT2 cells

Activin modulates the transcriptional response of LβT2 cells to gonadotropin-releasing hormone and alters cellular proliferation

H Zhang, JS Bailey, D Coss, B Lin… - Molecular …, 2006 - academic.oup.com
… The induction of the LHβ promoter by GnRH is mediated by … The gene encoding the FSHβ
subunit was not detectable by … as the estrogen, glucocorticoid, and progesterone receptors, …

Changes in pituitary gonadotropin subunits and hypothalamic Kiss-1 gene expression by administration of sex steroids in ovary-intact female rats

SS Yacca, H Kanasaki, T Tumurbaatar, Z Cairang… - Endocrine, 2024 - Springer
… The effects of sex steroids estradiol (E2), progesterone (P4), … inhibitory effect on CGA, LHβ,
and FSHβ subunit expression … study using LβT2 cells, Fshb subunit promoter activity as well …

Synergistic induction of follicle-stimulating hormone β-subunit gene expression by gonadal steroid hormone receptors and Smad proteins

VG Thackray, PL Mellon - Endocrinology, 2008 - academic.oup.com
… the transcription of LHβ and FSHβ subunit genes at the level … the repressive effect we observed
with progesterone. These … to the FSHβ promoter, we transfected LβT2 cells with a reporter …

Effects of sex steroids on the regulation of pituitary gonadotropins in the pituitary and hypothalamus

SS Yacca, H Kanasaki, T Tumurbaatar, Z Cairang… - 2023 - researchsquare.com
… how the sex steroids estradiol (E2), progesterone (P4), and … inhibitory effect on CGA, LHβ,
and FSHβ subunit expression … study using LβT2 cells, Fshb subunit promoter activity as well as …

Transcription of gonadotropin β subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones

P Melamed, MNA Kadir, A Wijeweera… - Molecular and cellular …, 2006 - Elsevier
estrogen receptor α (ERα) does associate with the LHβ gene … the progesterone receptor
(PR) increased rat FSHβ promoter … endogenous mouse LHβ gene promoter in LβT2 cells, while …

Gonadotropin hormones

UB Kaiser - The pituitary, 2011 - Elsevier
… start sites and utilize different promoters, accounting for their … levels of estradiol and
progesterone levels, initiating events for … , LHβ- and FSHβ-subunit mRNA levels through effects on …

Gonadotroph-specific expression of the human follicle stimulating hormone β gene in transgenic mice

TR Kumar, KG Schuff, KD Nusser, MJ Low - Molecular and cellular …, 2006 - Elsevier
… of the LHβ, FSHβ, and common α-gonadotropin subunits within … Although the LβT2 cell
line has recently emerged as an … of ovine, mouse and rat FSHβ subunit genes, the pattern of …

Gonadotropin-Releasing Hormone-Mediated Phosphorylation of Estrogen Receptor-α Contributes to fosB Expression in Mouse Gonadotrophs

J Chen, BS An, L Cheng, GL Hammond… - …, 2009 - academic.oup.com
… in mouse LβT2 pituitary cells because they express both FSHβ and LHβ subunit genes (30, …
is required for progesterone receptor transactivation of the gonadotropin α-subunit in αT3-1 …