The Potential Therapeutic Application of Simvastatin for Brain Complications and Mechanisms of Action
YM Vuu, A Kadar Shahib, M Rastegar - Pharmaceuticals, 2023 - mdpi.com
… , amongst its two groups, lipophilic statins have a higher ability … of simvastatin for 4 weeks in
Sprague–Dawley rats restored … significantly increased dopamine content in the striatum [168]…
Sprague–Dawley rats restored … significantly increased dopamine content in the striatum [168]…
Repeated ethanol exposure influences key enzymes in cholesterol and lipid homeostasis via the AMPK pathway in the rat prefrontal cortex
… study examined the dose- and time-response effects of acute … times per week from Monday
to Friday between 10:00 and 16:… to dopamine D 2 receptors, the dopamine reuptake inhibitor, …
to Friday between 10:00 and 16:… to dopamine D 2 receptors, the dopamine reuptake inhibitor, …
Reduced cholesterol is associated with the depressive-like behavior in rats through modulation of the brain 5-HT1A receptor
S Sun, S Yang, Y Mao, X Jia, Z Zhang - Lipids in Health and Disease, 2015 - Springer
… between cholesterol dysfunction and depressive symptoms, … Selective serotonin reuptake
inhibitors (SSRIs) are the first-… medial prefrontal cortex were significantly decreased in rats that …
inhibitors (SSRIs) are the first-… medial prefrontal cortex were significantly decreased in rats that …
A neurochemical heterogeneity of the rat striatum as measured by in vivo electrochemistry and microdialysis
BK Yamamoto, EA Pehek - Brain research, 1990 - Elsevier
… interaction between the density of dopaminergic innervation … striatum receive afferents from
the frontal cortex and insular … DOPAC levels decreased after amphetamine due to reuptake …
the frontal cortex and insular … DOPAC levels decreased after amphetamine due to reuptake …
Brain serotonin and dopamine transporter bindings in adults with high-functioning autism
K Nakamura, Y Sekine, Y Ouchi, M Tsujii… - Archives of general …, 2010 - jamanetwork.com
… E Selective serotonin reuptake inhibitors in autism: a review … prefrontal cortices with
methamphetamine-related psychiatric … the relationships between some of the clinical symptoms of …
methamphetamine-related psychiatric … the relationships between some of the clinical symptoms of …
Impact of traumatic brain injury on dopaminergic transmission
YH Chen, EYK Huang, TT Kuo, J Miller… - Cell …, 2017 - journals.sagepub.com
… Investigation of DAT levels in the rat frontal cortex and striatum after a CCI … DA release and
reuptake but also affects DA metabolic rate … Statin treatment could markedly reduce functional …
reuptake but also affects DA metabolic rate … Statin treatment could markedly reduce functional …
Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice
FK Ludka, LC Constantino, G Kuminek… - Pharmacology …, 2014 - Elsevier
… , po), a serotonin selective reuptake inhibitor (SSRI) was able to … frontal cortices' 5-HT content
when administered in the same … which statins can boost the SSRI antidepressant effect was …
when administered in the same … which statins can boost the SSRI antidepressant effect was …
Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine
AR Gilbert, GJ Moore, MS Keshavan… - Archives of general …, 2000 - jamanetwork.com
… reuptake inhibitor, paroxetine hydrochloride. … between patients with OCD (7.69 ± 1.31 cm
3 ) and controls (7.49 ± 1.10 cm 3 ) in our study, metabolic activity in ventral prefrontal cortex is …
3 ) and controls (7.49 ± 1.10 cm 3 ) in our study, metabolic activity in ventral prefrontal cortex is …
Dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administration
… Relationship between activation in the ventral striatum and … has been reported in the frontal
cortex, ostensibly reflecting … increased dopamine reuptake, whereas treatment of rat striatal …
cortex, ostensibly reflecting … increased dopamine reuptake, whereas treatment of rat striatal …
Metformin and fluoxetine improve depressive-like behavior in a murine model of Parkinsońs disease through the modulation of neuroinflammation, neurogenesis and …
IP Mendonça, IHR de Paiva, EP Duarte-Silva… - International …, 2022 - Elsevier
… IL-1β in the prefrontal cortex and iNOS levels in the hippocampus. Both … between
cholinergic and dopaminergic activity in the … reuptake inhibitors (SSRIs) and also has anti-inflammatory …
cholinergic and dopaminergic activity in the … reuptake inhibitors (SSRIs) and also has anti-inflammatory …