… causal effects of these kidney function markers. Using genetic data from the UK Biobank,
we recently carried out a one-sample MR study examining the causal effects of eGFRcys, …

… impact on our understanding of the genetic … of thyroid disorders in relation to regional brain
volumes, with an association found between hypothyroidism and reduced gray matter volume …

… For regional brain volumes, we found associations for volumes … hypothyroidism had also
been linked to changes of brain … This research has been conducted using the UK Biobank …

… brain volume was not altered, indicating that perinatal hypothyroidism irreversibly reduces
brain volume … The aim of the present study was to determine for the first time the effects of adult…

… in the UK Biobank cohort by examining the impact of oral … how sex differences in brain size
can be explained by differences … an important index of maximal brain size across the lifespan, …

… Additionally, in this study, we used the UK Biobank data, which is rich in both sample size
and type, to evaluate whether higher BMI is associated with lower subsequent cognitive …

… TSH with gray matter volume in their study was only … effect of maternal thyroid status on 5
child brain volume may therefore have been missed in our study due to the slightly later thyroid …

… transcript and direction of biological effect. In >400,000 UK Biobank participants, we conduct
… , is associated with a reduced risk of hypothyroidism in UK Biobank participants (OR 0.77 CI …

… Furthermore, general population twin studies suggest that additive genetic effects account
for 40% of the variance in measures of affect intensity and 25% of the variance in affective …

… causal effect of atrial fibrillation on brain volume phenotypes … solely consisted of the UK
Biobank cohort, we intentionally … thyroid disorder in the abovementioned 337,138 white British …