[HTML][HTML] Pathways explaining racial/ethnic and socio-economic disparities in brain white matter integrity outcomes in the UK Biobank study

J Weiss, MA Beydoun, HA Beydoun… - SSM-Population …, 2024 - Elsevier
… GWAS data from external or internal UK Biobank data. The Standard PRS Set (also … genetic
risk for AD), from the UK Biobank-free standard set of PRS which was then used as an effect

[HTML][HTML] The correlation between thyroid function, frontal gray matter, and executive function in patients with major depressive disorder

S Zhao, Y Xia, Y Huang, H Zou, X Wang… - Frontiers in …, 2021 - frontiersin.org
… gray matter volumes, which indicated that THs affect brain development (55). A large UK
Biobank study also provided evidence for the effect of THs on gray matter volumes in adults, …

Lower serum testosterone concentrations are associated with a higher incidence of dementia in men: the UK Biobank prospective cohort study

RJ Marriott, K Murray, L Flicker… - Alzheimer's & …, 2022 - Wiley Online Library
effect of these covariates, additional analyses were conducted including diabetes and thyroid
… The strengths of the present study include the size of the UK Biobank cohort, with a large …

The ageing thyroid: implications for longevity and patient care

D van Heemst - Nature Reviews Endocrinology, 2024 - nature.com
… Here, potential causes and consequences of the altered thyroid status observed in old
age and its association with longevity will be discussed. In about 5–20% of adults at least 65 …

[HTML][HTML] Effects of Body Mass Index on Brain Structures in the Elderly: Longitudinal Analyses

H Takeuchi, R Kawashima - Frontiers in Endocrinology, 2022 - frontiersin.org
… Additionally, in this study, we used the UK Biobank data, which is rich in both sample size
and type, to evaluate whether higher BMI is associated with lower subsequent cognitive …

Causal effects of atrial fibrillation on brain white and gray matter volume: a Mendelian randomization study

S Park, S Lee, Y Kim, S Cho, K Kim, YC Kim, SS Han… - BMC medicine, 2021 - Springer
… causal effect of atrial fibrillation on brain volume phenotypes … solely consisted of the UK
Biobank cohort, we intentionally … thyroid disorder in the abovementioned 337,138 white British …

Association of major depression, schizophrenia and bipolar disorder with thyroid cancer: a bidirectional two-sample mendelian randomized study

R Qiu, H Lin, H Jiang, J Shen, J He, J Fu - BMC psychiatry, 2024 - Springer
… This study aimed to investigate the potential causal effects of MDD, SCZ, BD, and … Of the
three GWASs, only the UK Biobank and the PGC publish summary statistics on genetic variation. …

The causal relationship between thyroid function, autoimune thyroid dysfunction and lung cancer: a mendelian randomization study

X Wang, X Liu, Y Li, M Tang, X Meng, Y Chai… - BMC Pulmonary …, 2023 - Springer
… In summary, hypothyroidism genetically had a protective causal association with lung
cancer. Furthermore, hypothyroidism had protective effects both on lung adenocarcinoma and …

[HTML][HTML] The causal relationship between major depression disorder and thyroid diseases: A Mendelian randomization study and mediation analysis

X Zhang, Q Lu, Y Luo, L Wang, Y Tian, X Luo - Journal of Affective …, 2024 - Elsevier
… We also aimed to clarify the indirect impact of MDD on thyroid … that thyroid function were
not genetically correlated with MDD in other populations. Second, the sample size of thyroid

[HTML][HTML] Investigating pleiotropy between depression and autoimmune diseases using the UK Biobank

KP Glanville, JRI Coleman, PF O'Reilly… - … psychiatry global open …, 2021 - Elsevier
size led us to combine thyroiditis and Gravesdisease, which … effects, we found little evidence
that shared genetic factors … autoimmune diseases in the UK Biobank. The limited shared …