[HTML][HTML] … D status and vitamin D supplements use with all-cause dementia, Alzheimer's disease, and vascular dementia: a UK Biobank based prospective cohort study

LJ Chen, S Sha, H Stocker, H Brenner… - The American Journal of …, 2024 - Elsevier
… large UK Biobank cohort study with a median follow-up of 13.6 years, we aimed to assess
the associations of serum vitamin D status … of the true effect estimates by our study. Moreover, …

Association of air pollution with postmenopausal breast cancer risk in UK Biobank

C Smotherman, B Sprague, S Datta… - … Cancer Research, 2023 - Springer
Study population Women in this study were selected from UK Biobank, an established
population-… However, we found a weaker effect of 2-year or 5-year lagged exposure for PM 10 …

An investigation of genetically determined telomere length and its impact on disease in UK Biobank

S Stoma - 2021 - figshare.le.ac.uk
… This study investigates genetically determined telomere length and its association with
age-… A genetic risk score was built within UK Biobank for each participant using the genetic

Genome-wide association study identifies genetic risk factors for spastic cerebral palsy

AT Hale, O Akinnusotu, J He, J Wang, N Hibshman… - …, 2021 - journals.lww.com
… in the UK Biobank and FinnGen, we perform the first genome-wide association study (GWAS…
(de novo or inherited) with large effect sizes, as well as identifying copy number variations …

Cognitive function in people with psychiatric and neurological disorders in UK Biobank

B Cullen - 2018 - theses.gla.ac.uk
studies in this thesis use data from the UK Biobank cohort. As described in detail in Chapter
3, UK Biobank … the overall effect of BD and other disorders on cognitive function, and the …

Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes

…, Estonian Biobank Research Team Esko Tõnu 1 … - Translational …, 2022 - nature.com
… DNA contributes large effect variants. We … status in UK Biobank, we still found significant
associations (P < 0.05, Table 1) with aSNPs related to the archaic haplotype of the UK Biobank

[HTML][HTML] Effects of hyperthyroidism on venous thromboembolism: A Mendelian randomization study

F Han, C Zhang, M Xuan, Z Xie, K Zhang… - … of Immunology Research, 2022 - hindawi.com
hypothyroidism, and hyperthyroidism were obtained from the ThyroidOmics Consortium and
the UK Biobank… variables, the casual effects of genetically predicted TSH and FT4 and hypo- …

Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases

S Yuan, L Wang, H Zhang, F Xu, X Zhou, L Yu, J Sun… - …, 2023 - thelancet.com
… loss-of-function variant with hypothyroidism, inflammatory bowel … with disease outcomes in
the UK Biobank study. We then … complement the genetic evidence of possible clinical effects. …

A genotype-first approach to exploring Mendelian cardiovascular traits with clear external manifestations

BM Wenger, N Patel, M Lui, A Moscati, R Do… - Genetics in …, 2021 - nature.com
… Thus, our results show that thyroid disease and autoimmune … and Genetics, National
Cancer Institute, Rockville, Maryland. This research has been conducted using the UK Biobank

The impact of age on genetic risk for common diseases

X Jiang, C Holmes, G McVean - PLoS genetics, 2021 - journals.plos.org
… , skin cancer, atherosclerotic heart disease, hypothyroidism and calculus of gallbladder, …
UK Biobank, a prospective study of 500,000 people, we show that there is a tendency for genetic