[HTML][HTML] Protein stoichiometry, structural plasticity and regulation of bacterial microcompartments

LN Liu, M Yang, Y Sun, J Yang - Current Opinion in Microbiology, 2021 - Elsevier
… proteinaceous shell and encapsulated enzymes that are … -associated microcompartments
(GRM), choline utilization (GRM2), … the underlying molecular mechanisms, these assembly and …

Heterologous Assembly of Pleomorphic Bacterial Microcompartment Shell Architectures Spanning the Nano‐to Microscale

BH Ferlez, H Kirst, BJ Greber, E Nogales… - Advanced …, 2023 - Wiley Online Library
… standing of the molecular mechanisms governing their self-… a broad distribution of particle
sizes ranging from ~30 – 200 … , with one or more smaller shells encapsulated within a larger …

[HTML][HTML] Microcompartment assembly around multicomponent fluid cargoes

L Tsidilkovski, F Mohajerani, MF Hagan - The Journal of chemical …, 2022 - pubs.aip.org
… RR and ɛ GG raises the number of encapsulated cargo particles N C , which asymptotically
approaches the … To elucidate mechanisms that control the amount and composition of cargo …

Mechanisms of scaffold-mediated microcompartment assembly and size control

F Mohajerani, E Sayer, C Neil, K Inlow, MF Hagan - ACS nano, 2021 - ACS Publications
… Thus, understanding the mechanisms that control cargo encapsulationparticles and their
packaging within an assembling protein shell. While motivated by bacterial microcompartments

Bacterial microcompartments: catalysis-enhancing metabolic modules for next generation metabolic and biomedical engineering

H Kirst, CA Kerfeld - BMC biology, 2019 - Springer
… There is no known mechanism for proteins to cross the BMC … the determinants of enzyme
encapsulation. However, … ochraceum forms homogeneous particles of 40 nm diameter […

Structure of a minimal α-carboxysome-derived shell and its utility in enzyme stabilization

YQ Tan, S Ali, B Xue, WZ Teo, LH Ling, MK Go… - …, 2021 - ACS Publications
Encapsulation peptide sequences that facilitate loading of … the formation of shell-like particles
observed. We term these … possible molecular mechanism contributing to encapsulation by …

Innate and Engineered Attributes of Bacterial Microcompartments for Applications in Bio-Material Science

S Sinha, SM Rose, A Radhakrishnan - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
… part of bacterial carbon dioxide concentrating mechanisms (… encapsulated enzymatic cargo
with high thermal and pH stability. Another important property of bacterial microcompartments

Formation and function of bacterial organelles

C Greening, T Lithgow - Nature Reviews Microbiology, 2020 - nature.com
… This would encapsulate all recognized organelles but could … Detailed genetic and
structural studies suggest that the β-… Each particle contains 240 encapsulin protomers, which …

Prokaryotic Organelles: Bacterial Microcompartments in E. coli and Salmonella

KL Stewart, AM Stewart, TA Bobik - EcoSal Plus, 2020 - Am Soc Microbiol
… of a metabolic pathway encapsulated within a selectively … , protein targeting, and the
mechanisms that underlie selective … the complex nature of these particles and have motivated …

Bacterial microcompartments as a next-generation metabolic engineering tool: utilizing nature's solution for confining challenging catabolic pathways

L Doron, CA Kerfeld - Biochemical Society Transactions, 2024 - portlandpress.com
structural studies demonstrated that the architectural plasticity of recombinantly assembled
shell particles … with other native and synthetic encapsulation mechanisms to target multiple …