… to hypoxia results in regulated ATP release from VVEC. In turn… Injection of the GPCR-G q /G
i -coupled ligand, PAF into rat … tissue and in turn can lead to EC apoptosis, down regulation of …

… cytokines and oxidative stress in vascular endothelial cells [1,2]… of Ang II; we go deeper into
the potential mechanisms of this … Simultaneously, down-regulation of the production of NO …

… damage, hypoxia and cytokine inflammatory stimulation. In response to inflammatory stimuli
mainly mediated by NF-kB activation, the vascular endothelium … inflammatory ligand serum …

… antioxidants should protect vascular endothelium specifically … in response to hypoxia-induced
stress (flow mediated dilation, … and their respective vascular ligands. Among them, VCAM-1 …

… in vascular endothelial cells, smooth muscle cells and … H 2 O 2 via the down-regulation
of the oxidant genes such as … also protected endothelial progenitor cells from hypoxia-induced …

… by a variety of cellular stressors, such as hypoxia, reactive … autophagy is accompanied by
down-regulation of the eNOS … of the autophagic process impairs ligand-stimulated release of …

… HRE, hypoxia-response element; VEGF, vascular endothelial growth factor; ET-1, endothelin-1…
HER2 overexpression or HER2 ligand heregulin stimulation induces VEGF expression in …

… of inflammation and vascular injury. PGI 2 is produced by endothelial cells and influences
… PGI 2 acts mainly on the prostacyclin (IP) receptor, but because of receptor homology, PGI 2 …

… male rats 7 even though these rats express high levels of ERα … play a major role in mediating
the cardiovascular protective … acts as an ERβ ligand at nanomolar concentrations and …

… hypoxia, we have characterized expression of VEGF and its … expansion, and possible
mechanisms include VEGF-induced … In this study, we isolated rat neonatal cardiac myocytes and …