Nitric-oxide synthase trafficking inducer is a pleiotropic regulator of endothelial cell function and signaling
S Chakraborty, R Ain - Journal of Biological Chemistry, 2017 - ASBMB
… example, vascular endothelial growth factor (VEGF)-mediated … for NOSTRIN-induced
down-regulation of endothelial cell proteins. … Mouse and rat orthologs share an 81–82% sequence …
down-regulation of endothelial cell proteins. … Mouse and rat orthologs share an 81–82% sequence …
Recent insights on the mechanisms of liver preconditioning
R Carini, E Albano - Gastroenterology, 2003 - Elsevier
… a variety of metabolites and ligands including adenosine, NO, … the tolerance against
hypoxia/reperfusion damage.37 Thus, … ischemic preconditioning is the down-regulation of …
hypoxia/reperfusion damage.37 Thus, … ischemic preconditioning is the down-regulation of …
Endothelial dysfunction in obesity
A Engin - Obesity and lipotoxicity, 2017 - Springer
… adipose tissue might be the result of the down-regulation of both … (oxLDL) and adipose
tissue hypoxia are discussed. … protein regulates the vascular endothelial cell function in obese …
tissue hypoxia are discussed. … protein regulates the vascular endothelial cell function in obese …
Dual ETA/ETB vs. selective ETA endothelin receptor antagonism in patients with pulmonary hypertension
CF Opitz, R Ewert - European Journal of Clinical Investigation, 2006 - Wiley Online Library
… mode of the ETB receptor from down-regulation to recycling in … by vascular endothelial cells.
Nature 1988;332:411–5. … orally active endothelin receptor antagonist in hypoxic rats. Am J …
Nature 1988;332:411–5. … orally active endothelin receptor antagonist in hypoxic rats. Am J …
Non-coding RNA regulation of endothelial and macrophage functions during atherosclerosis
… damage, hypoxia and cytokine inflammatory stimulation. In response to inflammatory stimuli
mainly mediated by NF-kB activation, the vascular endothelium … inflammatory ligand serum …
mainly mediated by NF-kB activation, the vascular endothelium … inflammatory ligand serum …
Autophagy in vascular endothelial cells
F Jiang - Clinical and Experimental Pharmacology and …, 2016 - Wiley Online Library
… by a variety of cellular stressors, such as hypoxia, reactive … autophagy is accompanied by
down-regulation of the eNOS … of the autophagic process impairs ligand-stimulated release of …
down-regulation of the eNOS … of the autophagic process impairs ligand-stimulated release of …
TSP1–CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction
NM Rogers, M Sharifi-Sanjani, M Yao… - Cardiovascular …, 2017 - academic.oup.com
… with down regulation of the transcription factor cell homolog … Endothelin-1 (ET-1), via
interactions with endothelin receptor … pulmonary arterial endothelial cells (hPAEC) to hypoxia (FiO …
interactions with endothelin receptor … pulmonary arterial endothelial cells (hPAEC) to hypoxia (FiO …
Effects of insulin resistance on endothelial progenitor cells and vascular repair
RM Cubbon, MB Kahn, SB Wheatcroft - Clinical Science, 2009 - portlandpress.com
… that dysfunction of the vascular endothelium represents the earliest … tissues is driven largely
by tissue hypoxia [58]. Interaction … to abrogate the down-regulation of tissue VEGF production …
by tissue hypoxia [58]. Interaction … to abrogate the down-regulation of tissue VEGF production …
Hypoxia: the force that drives chronic kidney disease
Q Fu, SP Colgan, CS Shelley - Clinical medicine & research, 2016 - Marshfield Clinic
… by intrarenal administration of vascular endothelial growth factor … CC motif ligand 2 and
C-X3-C motif ligand 1. These … modifications that up-regulate expression of endothelin 1, thus, …
C-X3-C motif ligand 1. These … modifications that up-regulate expression of endothelin 1, thus, …
Hypoxia-inducible factors not only regulate but also are myeloid-cell treatment targets
L Kling, A Schreiber, KU Eckardt… - Journal of leukocyte …, 2021 - academic.oup.com
… B scavenger receptor CD36 and its ligand thrombospondin-1 … , combined PHD down-regulation
and up-regulation of HIF … Subsequently, endothelin receptor stimulation activated …
and up-regulation of HIF … Subsequently, endothelin receptor stimulation activated …