[HTML][HTML] Pathophysiology of acute kidney injury

DP Basile, MD Anderson, TA Sutton - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
… trigger conversion from transient hypoxia to intrinsic renal failure. Injury to kidney cells can
… The nature of the recovery response is mediated by the degree to which sublethal cells can …

Hypoxia causes downregulation of 11β‐hydroxysteroid dehydrogenase type 2 by induction of Egr‐1

CD Heiniger, RM Kostadinova, MK Rochat… - The FASEB …, 2003 - Wiley Online Library
mechanism to maintain sodium and potassium balance in the presence of the missing MR
ligand … RT of Erg-1 message from cell cultures and kidneys from rats was performed in RT …

Puerarin: a review of pharmacological effects

YX Zhou, H Zhang, C Peng - Phytotherapy Research, 2014 - Wiley Online Library
protect kidney against oxidative damage by down-regulation … and promoted hypoxia-evoked
apoptosis in rat PASMCs, … activity and number of vascular endothelial cells and elevated the …

[HTML][HTML] Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear …

W Lim, Y Park, J Cho, C Park, J Park, YK Park… - Breast Cancer …, 2011 - Springer
Vascular endothelial growth factor (VEGF) was measured in … mediated gene transcription
through ARNT down-regulation. … ERβ on hypoxia-mediated response is independent of ligand. …

Peroxisome proliferator-activated receptorligands regulate endothelial membrane superoxide production

J Hwang, DJ Kleinhenz, B Lassegue… - … of Physiology-Cell …, 2005 - journals.physiology.org
mechanisms by which PPAR-γ ligands alter endothelial·NO … NADPH oxidase activity in a rat
model of hypertension (14) and … gene expression in vascular endothelial cells that results in …

CircRNA–miRNA interactions in atherogenesis

KL Tong, KE Tan, YY Lim, XY Tien, PF Wong - Molecular and cellular …, 2022 - Springer
… One of the most common mechanism of action of circRNAs … The vascular endothelium acts
as a barrier between … species (ROS), endothelin-1 (ET-1), and cell adhesion molecule (CAM) …

Vasoactive factors and diabetic retinopathy: vascular endothelial growth factor, cycoloxygenase-2 and nitric oxide

JL Wilkinson-Berka - Current pharmaceutical design, 2004 - ingentaconnect.com
… localised hypoxia which is viewed to up-regulate injurious … -2 in vascular endothelium
rendering its ligands less available to … growth factor and downregulation of pigment epithelium-…

Molecular pharmacology and pathophysiological significance of endothelin

K Goto, H Hama, Y Kasuya - The Japanese Journal of Pharmacology, 1996 - jstage.jst.go.jp
vascular endothelial cells are the major source of endothelin-… been proposed as the mechanism
for down-regulation (78). … orally active endothelin receptor antagonist in hypoxic rats. Am …

[HTML][HTML] The dual roles of autophagy and the GPCRs-mediating autophagy signaling pathway after cerebral ischemic stroke

W Hou, Y Hao, L Sun, Y Zhao, X Zheng, L Song - Molecular Brain, 2022 - Springer
… of a variety of hypoxia-responsive genes, such as vascular endothelial growth factor, … infarct
volume in rats exposed to transient focal cerebral ischemia [70]. Down-regulation of beclin-1 …

Dysregulation of Claudin-5 in HIV-induced interstitial pneumonitis and lung vascular injury. Protective role of peroxisome proliferator–activated receptor

H Li, S Singh, R Potula, Y Persidsky… - American journal of …, 2014 - atsjournals.org
down-regulation of endothelial TJ proteins and injury to the pulmonary vascular endothelium
… Studies in rat models of pulmonary hypertension and hypoxia showed that rosiglitazone …