Antioxidant defences in rat, pig, guinea pig, and human hearts: comparison with xanthine oxidoreductase activity
M Janssen, P van der Meer… - Cardiovascular …, 1993 - academic.oup.com
… the effect of xanthine oxidoreductase on ischaemiareperfusion … differences in xanthine
oxidoreductase activity in various … Explanted hearts of patients in end stage heart failure due to …
oxidoreductase activity in various … Explanted hearts of patients in end stage heart failure due to …
Acute effects of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in pacing induced heart failure
… xanthine oxidase inhibition with febuxostat enhances left ventricular (LV) function and
improves myocardial high energy phosphates (HEP) in dogs with pacing-induced heart failure (…
improves myocardial high energy phosphates (HEP) in dogs with pacing-induced heart failure (…
Regulation of endothelial cell xanthine dehydrogenase xanthine oxidase gene expression by oxygen tension
PM Hassoun, FS Yu, AL Shedd… - … of Physiology-Lung …, 1994 - journals.physiology.org
… that xanthine dehydrogenase/xanthine oxidase (XD/XO) activities of bovine endothelial cells
(EC) … transport, we failed to find stimulation of XD/XO activity or gene expression (results not …
(EC) … transport, we failed to find stimulation of XD/XO activity or gene expression (results not …
Regulation of xanthine oxidoreductase protein expression by hydrogen peroxide and calcium
JS McNally, A Saxena, H Cai, S Dikalov… - … , and vascular biology, 2005 - Am Heart Assoc
… (ROS) is xanthine oxidase (XO), an enzyme that uses xanthine and hypoxanthine as …
injury, endothelial dysfunction associated with congestive heart failure, atherosclerosis, and left …
injury, endothelial dysfunction associated with congestive heart failure, atherosclerosis, and left …
Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment
L Zhao, BM Roche, JL Wessale, A Kijtawornrat, JL Lolly… - Life Sciences, 2008 - Elsevier
… Xanthine oxidase (XO) expression is increased in the failing heart, and animal studies in … )
function and myocardial oxygen efficiency in the failing heart. The purpose of this study was to …
function and myocardial oxygen efficiency in the failing heart. The purpose of this study was to …
Allopurinol, xanthine oxidase, and cardiac ischemia
BE Lee, AH Toledo, R Anaya-Prado… - Journal of …, 2009 - journals.sagepub.com
… on ischemic hearts as well as those with added chronic heart failure. Increased levels of …
dysfunctions are common characteristics experienced during cardiac ischemia and reperfusion (I…
dysfunctions are common characteristics experienced during cardiac ischemia and reperfusion (I…
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress
J George, AD Struthers - Vascular health and risk management, 2009 - Taylor & Francis
… In dogs with pacing-induced heart failure, allopurinol improved myocardial contractility
and eff iciency in oxygen utilization, prevented increases in systemic vasoconstriction and …
and eff iciency in oxygen utilization, prevented increases in systemic vasoconstriction and …
Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice
Y Tanaka, T Nagoshi, A Yoshii, Y Oi… - Free Radical Biology …, 2021 - Elsevier
… the cardiac tissue UA level might increase in the failing heart … that cardiac tissue XDH activity
was significantly increased in … significantly reduced cardiac XDH activity (Supplementary Fig…
was significantly increased in … significantly reduced cardiac XDH activity (Supplementary Fig…
Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy
… Note the enhanced expression of NADPH oxidase subunits in the diabetic mice, which is …
This coupled with the beneficial effects of ALP in various animal models of heart failure, also …
This coupled with the beneficial effects of ALP in various animal models of heart failure, also …
Increased plasma xanthine oxidoreductase activity deteriorates coronary artery spasm
K Watanabe, T Shishido, Y Otaki, T Watanabe… - Heart and Vessels, 2019 - Springer
… Xanthine oxidoreductase (XOR) plays a pivotal role in producing both … activity and CAS
has not been elucidated. The aim of this study was to investigate whether plasma XOR activity is …
has not been elucidated. The aim of this study was to investigate whether plasma XOR activity is …