… Note the enhanced expression of NADPH oxidase subunits in the diabetic mice, which is …
This coupled with the beneficial effects of ALP in various animal models of heart failure, also …

… Xanthine oxidoreductase (XOR) plays a pivotal role in producing both … activity and CAS
has not been elucidated. The aim of this study was to investigate whether plasma XOR activity is …

… These experiments tested the hypothesis that xanthine oxidase (XO) contributes to MV-…
enhanced cardiac muscle twitch tension in spontaneously hypertensive, heart failure-prone …

… As such, inhibition of XOR has emerged as a potential therapeutic target in the treatment of
heart failure (4). Despite these key roles and pathophysiologic implications, relatively little is …

… These results underscore the significance of reactive oxygen species as important
pathophysiological mediators in ischemic heart failure and point toward xanthine oxidase as an …

… with other cardiovascular risk factors or heart failure. Furthermore, we and others have …
activity is markedly increased in patients with coronary disease, carotid stenosis, or heart failure …

… to alter xanthine oxidoreductase (XOR) activity leading to … conditions also expresses
oxidase activity leading to both O 2 ·… To account for potential technical failure, we increased this …

… compared to analyse the protection given in heart failure, chronic kidney diseases, and other
… an increased expression of adipogenesis genes [55]. Additionally, XOR null mice exhibited …

… Xanthine oxidoreductase (XOR) is a complex … the hydroxylation of hypoxanthine to xanthine
and of xanthine to urate. Until … failed to confirm many aspects of this early work. Thus, XOR …

… Increased UA levels may be an indicator of up-regulated activity of xanthine oxidase, a …
for increased mortality or hospital re-admission for heart failure. In turn, the use of allopurinol …