Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming
FR D'Alessio, JM Craig, BD Singer… - … of Physiology-Lung …, 2016 - journals.physiology.org
… Therefore, we suggest a potential IL-4-mediated benefit would be to enhance macrophage
efferocytosis of apoptotic neutrophils and accelerate experimental ALI resolution. …
efferocytosis of apoptotic neutrophils and accelerate experimental ALI resolution. …
[HTML][HTML] … Research in Acute Lung Injury and Pulmonary Fibrosis: Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming
FR D'Alessio, JM Craig, BD Singer… - … of Physiology-Lung …, 2016 - ncbi.nlm.nih.gov
… Therefore, we suggest a potential IL-4-mediated benefit would be to enhance macrophage
efferocytosis of apoptotic neutrophils and accelerate experimental ALI resolution. …
efferocytosis of apoptotic neutrophils and accelerate experimental ALI resolution. …
Efficacy of pulmonary transplantation of engineered macrophages secreting IL-4 on acute lung injury in C57BL/6J mice
H Liu, Y He, C Lu, P Zhang, C Zhou, Y Ni, W Niu… - Cell Death & …, 2019 - nature.com
… ALI or ARDS and failure to resolve ongoing inflammation … , alveolar macrophages underwent
increased necrotic cell death, … The experiments were conducted using a protocol approved …
increased necrotic cell death, … The experiments were conducted using a protocol approved …
Inhibition of EZH2 prevents acute respiratory distress syndrome (ARDS)-associated pulmonary fibrosis by regulating the macrophage polarization phenotype
X Bao, X Liu, N Liu, S Zhuang, Q Yang, H Ren… - Respiratory …, 2021 - Springer
… an increased expression of EZH2 and H3K27me3 in the lung … epigenetic reprogramming
contributes to macrophage … Therefore, our in vitro and in vivo experiments indicated that …
contributes to macrophage … Therefore, our in vitro and in vivo experiments indicated that …
The role of macrophages and alveolar epithelial cells in the development of ARDS
H Tao, Y Xu, S Zhang - Inflammation, 2023 - Springer
… resolution and tissue repair initiate a “pro-resolution” CD11b low macrophages, which are
characterized by the enhanced … The reprogrammed macrophages are thus polarized upon …
characterized by the enhanced … The reprogrammed macrophages are thus polarized upon …
Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome
X Chen, J Tang, W Shuai, J Meng, J Feng, Z Han - Inflammation Research, 2020 - Springer
… by increased non-hydrostatic extravascular lung water, … or vice versa (repolarization or
reprograming) could be novel … of ALI/ARDS, lung macrophages shift into the M1 phenotype …
reprograming) could be novel … of ALI/ARDS, lung macrophages shift into the M1 phenotype …
The role of macrophages in the development of acute and chronic inflammatory lung diseases
JW Lee, W Chun, HJ Lee, JH Min, SM Kim, JY Seo… - Cells, 2021 - mdpi.com
… the acute and chronic experimental animal models. Thus, this … of M1/M2 macrophage
roles in the development of ALI, ARDS, … indicated that increased levels of macrophage-associated …
roles in the development of ALI, ARDS, … indicated that increased levels of macrophage-associated …
Alveolar macrophage transcriptional programs are associated with outcomes in acute respiratory distress syndrome
ED Morrell, PK Bhatraju, CR Mikacenic… - American journal of …, 2019 - atsjournals.org
… We next sought to better capture the dynamics of gene expression during … Enhanced
resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming. Am J …
resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming. Am J …
NETs promote ALI/ARDS inflammation by regulating alveolar macrophage polarization
C Song, H Li, Y Li, M Dai, L Zhang, S Liu, H Tan… - Experimental cell …, 2019 - Elsevier
… promote ARDS inflammation during the acute phase by promoting macrophage polarization
to … are reduced or not, we can speculate that M1 macrophages ratio maybe increased during …
to … are reduced or not, we can speculate that M1 macrophages ratio maybe increased during …
Macrophages in lung injury, repair, and fibrosis
P Cheng, S Li, H Chen - Cells, 2021 - mdpi.com
… cell-based therapeutic method for ARDS [67]. MSC-derived … -culture experiment indicated
that macrophages enhance AT2 … ALI and lung repair by reprogramming macrophages to the …
that macrophages enhance AT2 … ALI and lung repair by reprogramming macrophages to the …