… We reported that IgG titers against three EGFR-derived peptides, EGFR 481-500 , EGFR 721…
induced PD-L1 expression in human bronchial epithelial cell lines, and that EGFR inhibitors …

… for cancer therapy with the EGFR/HER2 inhibitor 5 approved for treatment of advanced, …
known from HDAC inhibitors like 1 or 3, we obtained selective inhibitors for both targets with …

… EGFR inhibitor(erlotinib) and IGF-1R inhibitor (AEW-541) and our novel small molecule dual
… signaling pathways comprising growth factors like EGFR, PDGFRA (platelet derived growth …

… EGFR coding sequence mutations and correlated these findings with response to treatment
with the EGFR inhibitors … for total EGFR was a mouse monoclonal antibody obtained from BD …

… growth factors, particularly, vascular epidermal growth factor (… growth factor, platelet-derived
endothelial cell growth factor … these EGFR inhibitors as second and third-line therapies are …

… -derived cell lines (25). Augmented activity of membrane-associated tyrosine kinases, such
as EGFR, HER-2, and platelet-derived growth factor receptor… , treatment with EGFR inhibitors, …

… therapy (ie, first-generation epidermal growth factor receptor [… In a handful of cases, rebiopsy
of growing tumors has obtained … Another new EGFR inhibitor is AP26113. This drug was …

… counteracts the antiproliferative effects of EGFR inhibitors in human glioblastoma cells in
vitro[… obtained by the combination of anti-EGFR agents with other anti signalling agents, such as …

… the most recent data of anti-EGFR therapy in metastatic CRC. … cetuximab, the only EGFR
inhibitor that is currently approved … -2 (COX-2), c-kit, and platelet-derived growth factor receptor. …

… of tyrosine kinases associated with Bcr-Abl and c-kit and the platelet-derived growth factor
receptor tyrosine kinase. Imatinib was launched in the US in May 2001 for the treatment of …