… The orthotopic nude mice model of highly metastatic HCC was … In our previous animal model
study, we investigated the … such as sorafenib, sunitinib, brivanib, cetuximab, erlotinib and …

… the development of the disease in rat models[198]. Furthermore, … or in combination with
Sorafenib or Erlotinib in patients with … orthotopic human HCC xenografts results in reduced tumor …

… sorafenib in an orthotopic model of human hepatocellular … kinase inhibitors such as erlotinib
with rapalogs based on … inhibition in a rat model of hepatocellular carcinoma. J. Hepatol. …

… However, to date, no other investigated potential drugs (eg, sunitinib, erlotinib) including …
benefit over sorafenib in advanced HCC patients [11,12,13,14]. However, sorafenib has been …

… HCC patients who underwent orthotopic liver transplantation … to sorafenib and decreased
the frequency of liver cancer stem … using erlotinib and bevacizumab showed similar anti-cancer …

… by combining with sorafenib in anti-hepatocellular carcinoma (… 2.15 cells and tumor growth
of orthotopic HCC SD rats, but the … cancer, bevacizumab in colon cancer, and erlotinib in lung …

… orthotopic (into the mouse liver). In the case of orthotopic models, sophisticated animal imaging
platforms may be required for accurate … Sorafenib in advanced hepatocellular carcinoma …

… We further observed the effects of NZ001 and sorafenib … -6 orthotopic mice model, we
found that inhibition of VEGF signaling by multitargeted RTK inhibitor sorafenib slowed tumor …

… It was also reported that sorafenib induces tumor cell death via various MAPK-independent …
as displaying anti-HCC activity in an orthotopic HCC animal model [93]. This activity was …

… Erlotinib is a tyrosine kinase inhibitor targeting EGFR, which … of tumor cells in transgenic
and orthotopic mouse models. … in hepatocellular carcinoma and of its treatment with sorafeNib) …