Selective loss of estrogen receptor β in malignant human colon

EF Foley, AA Jazaeri, MA Shupnik, O Jazaeri, LW Rice - Cancer Research, 2000 - AACR
… four colon adenocarcinoma cell … estrogen replacement therapy against colon cancer may
be mediated by ER-β. The role of estrogen and antiestrogens in the pathogenesis of colorectal

Estrogen receptor-β signaling modulates epithelial barrier function

M Looijer-van Langen, N Hotte… - American Journal …, 2011 - journals.physiology.org
bowel disease (IBD) pathology and disease course. Estrogen receptor-β (ERβ) is the most
abundant estrogen … models of colitis and colon of patients with inflammatory bowel disease. …

Control of colon cancer development and progression by selected estrogen receptor modulators

V Martineti, S Silvestri, F Tonelli… - Expert review of …, 2008 - Taylor & Francis
… available colon adenocarcinoma cell lines substantially confirmed its absence or its very
low expression, with variable levels of ERβ depending on the different cell line Citation[35–38]. …

Expression of hormone receptors, cathepsin D, and HER-2/neu oncoprotein in normal colon and colonic disease

S Galandiuk, S Miseljic, AR Yang, M Early… - Archives of …, 1993 - jamanetwork.com
… This soluble protease was determined byenzyme immunoas¬ say of the same cytosol used
for the estrogen receptor and progestin receptor analyses. Cathepsin D was expressed as …

Colorectal cancer and inflammatory bowel disease: epidemiology, risk factors, mechanisms of carcinogenesis and prevention strategies

JK Triantafillidis, G Nasioulas… - Anticancer research, 2009 - ar.iiarjournals.org
… dysplasia and finally to invasive adenocarcinoma, although colorectal cancer can arise without
… The type A (estrogen receptor) occurs as a function of age and is found on normal colon

[图书][B] Molecular mechanisms of estrogen receptor beta action in colorectal carcinogenesis

DNV Saleiro - 2013 - search.proquest.com
… into a benign adenoma and then into an adenocarcinoma (“). In contrast, CAC does …
inflammation of the colonic epithelium ("). Thus, CAC is associated with inflammatory bowel disease

Estrogen and progesterone receptors in human colorectal tumour cells (study of 70 cases)

G Bracali, AM Caracino, F Rossodivita… - … journal of biological …, 1988 - journals.sagepub.com
estrogen receptors proved to be identical for the two sexes (28.5%), but the percentages of
progesterone receptors were different… of estrogen receptor in human colon cancer tissue with …

Oestrogen and the colon: potential mechanisms for cancer prevention

R Kennelly, DO Kavanagh, AM Hogan… - The lancet oncology, 2008 - thelancet.com
… typically have less aggressive disease. The discovery of a second oestrogen receptor (ERβ) …
alpha and beta in advanced gastric adenocarcinoma: correlation with prothymosin alpha …

Estrogen receptor α variant ERα46 mediates growth inhibition and apoptosis of human HT-29 colon adenocarcinoma cells in the presence of 17β-oestradiol

H Jiang, R Teng, Q Wang, X Zhang, H Wang… - Chinese medical …, 2008 - mednexus.org
… esEogen receptor … studies have shown that estrogen receptor B(ER[3)“and several splice
variants of ERⅡand ERB“.6 are involved in estrogen signaling.An exon一1 truncated ER5 …

The prognostic and therapeutic role of hormones in colorectal cancer: a review

S Nikolaou, S Qiu, F Fiorentino, S Rasheed… - Molecular biology …, 2019 - Springer
… forms of oestrogen receptors: ERα, ERβ and G-protein coupled oestrogen receptor (GPR30) …
GHSR1 can be a target for novel future treatment for early colorectal adenocarcinoma [59]. …