[HTML][HTML] Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt

EA Ozer, JP Allen, AR Hauser - BMC genomics, 2014 - Springer
… Using these genomes, we showed that AGEnt performed well … are human clinical isolates
from diverse body sites. The … 52 such regions they designated as Regions of Genomic Plasticity

[HTML][HTML] Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world

JC Galán, F González-Candelas, JM Rolain… - Frontiers in …, 2013 - frontiersin.org
… New sequencing platforms have revealed that our old concept … gene, present in the genome
of Pseudomonas aeruginosa … However, there are more clinical isolates carrying the D240G …

The Accessory Genome of Pseudomonas aeruginosa

VL Kung, EA Ozer, AR Hauser - Microbiology and molecular …, 2010 - Am Soc Microbiol
… pKLC102, a widely distributed 104-kb ICE first identified in P. … Portions of this island are
present in 85% of clinical isolates. … to reveal novel niche-specific accessory genetic elements …

[HTML][HTML] Emergence of Carbapenem Resistance Due to the Novel Insertion Sequence ISPa8 in Pseudomonas aeruginosa

RC Fowler, ND Hanson - PLoS One, 2014 - journals.plos.org
… of carbapenem resistance when a clinical isolate of P. … of the oprD gene from PA42
showed 99% similarity to oprD from P. … genomic plasticity and participate in the evolution of P. …

[HTML][HTML] In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs

P Bielecki, J Puchałka, ML Wos-Oxley, H Loessner… - PloS one, 2011 - journals.plos.org
… profiles also differ between the clinical isolates and the control … while the genomic contents
and plasticity of nosocomial P. … distribution were available, asymptotical Monte Carlo p-values …

Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts

S Damkiær, L Yang, S Molin… - Proceedings of the …, 2013 - National Acad Sciences
… in a highly successful Pseudomonas aeruginosa lineage (DK2… , the comparison showed
a large overlap of 700 genes, of … of gene expression as observed in the clinical isolate, …

Parallel evolution and local differentiation in quinolone resistance in Pseudomonas aeruginosa

A Wong, R Kassen - Microbiology, 2011 - microbiologyresearch.org
… of these genes has been reported in a clinical isolate of P. … resistance, considerable effort
has been devoted to identifying … to plasticity, genetic approaches should help to identify genes

Genotypes, carbapenemase carriage, integron diversity and oprD alterations among carbapenem-resistant Pseudomonas aeruginosa from Russia

Y Bocharova, T Savinova, A Lazareva… - International journal of …, 2020 - Elsevier
Pseudomonas aeruginosa genomic plasticity is conferred by … In total, 145 CRPA clinical
isolates were examined. … of the examined MBL genes was detected among ST357/ST2592 P. …

[HTML][HTML] High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs

E Rossi, M Falcone, S Molin, HK Johansen - Nature communications, 2018 - nature.com
… reference strain PA14 and clinical isolates were identified (Fig. 2a … Thus, HCA showed that
separation based on the genetic … a certain degree of gene expression plasticity, through which …

Role of horizontal gene transfer in the evolution of Pseudomonas aeruginosa virulence

X Qiu, BR Kulasekara, S Lory - Microbial pathogenomics, 2009 - karger.com
… segments represent regions of genomic plasticity (RGP) and … revealed that there was no
obvious association between any … organisms are as virulent as clinical isolates. In the case of …