Within-Host Adaptation Mediated by Intergenic Evolution in Pseudomonas aeruginosa

SMH Khademi, P Sazinas… - Genome Biology and …, 2019 - academic.oup.com
… Our study reveals that adaptive intergenic mutations represent … We next analyzed the genomic
distribution of the identified … the additional variants found in the clinical isolates) and in a …

[HTML][HTML] Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype

JG Thöming, J Tomasch, M Preusse, M Koska… - npj Biofilms and …, 2020 - nature.com
Clinical isolates exhibited a large diversity of biofilm … of microscopy images, we identified
clusters of strains that share … The biofilms of clinical isolates belonging to cluster A showed

[HTML][HTML] Genome Plasticity and Polymorphisms in Critical Genes Correlate with Increased Virulence of Dutch Outbreak-Related Coxiella burnetii Strains

R Kuley, E Kuijt, MA Smits, HIJ Roest… - Frontiers in …, 2017 - frontiersin.org
… the large outbreak, in order to identify genomic signatures … Novel genes, potentially
associated with increased bacterial … Our study showed a large number of mutations in membrane …

[HTML][HTML] Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa

Y Wang, L Gao, X Rao, J Wang, H Yu, J Jiang… - Scientific reports, 2018 - nature.com
… opportunistic pathogen is the genetic plasticity and the great … To thoroughly identify the
pathogenic determinants in bj13 … Our data did not reveal whether specific lasR mutants were …

[HTML][HTML] Complete Genome Analysis of Three Acinetobacter baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements

L Zhu, Z Yan, Z Zhang, Q Zhou, J Zhou, EK Wakeland… - PloS one, 2013 - journals.plos.org
… Acinetobacter baumannii genomes revealed extensive and dynamic genome organizations,
… , we identified 1,119 conserved orthologous proteins among all 14 Acinetobacter isolates

[HTML][HTML] Pseudomonas aeruginosa Population Structure Revisited

…, B Pot, P Cornelis, M Zizi, J Van Eldere, P Deschaght… - PloS one, 2009 - journals.plos.org
… We revealed a network of relationships between all analyzed … of 19 environmental and
clinical isolates revealed a net-like … plasticity and contains a high number of unfixed genes. Shen …

[HTML][HTML] Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic …

KA Simanek, JE Paczkowski - Microorganisms, 2022 - mdpi.com
… is likely the consequence of the relatively large genome of P. … A study of four clinical
isolates showed a time-dependent … aeruginosa isolates in Nigeria identified 50% resistance to …

Analysis of Genome Plasticity in Pathogenic and Commensal Escherichia coli Isolates by Use of DNA Arrays

U Dobrindt, F Agerer, K Michaelis, A Janka… - Journal of …, 2003 - Am Soc Microbiol
… to assess the distribution of these genes or their homologues among the pathogenic …
detected in other, even commensal, isolates can be due to similarity or identity to genes or gene

Pseudomonas aeruginosa renews its virulence factors

P Huber, P Basso, E Reboud… - Environmental …, 2016 - Wiley Online Library
… behavior of some clinical isolates. Here, we review the … Belkum et al., 2015) revealed
the existence of a third group of … ) have been identified in a region of genome plasticity (RGP69). …

[HTML][HTML] Spontaneous and evolutionary changes in the antibiotic resistance of Burkholderia cenocepacia observed by global gene expression analysis

A Sass, A Marchbank, E Tullis, JJ LiPuma… - Bmc Genomics, 2011 - Springer
… Both known and novel genes involved in efflux, antibiotic … known to induce the Pseudomonas
aeruginosa MexCD-OprJ … stably expressed control gene as it showed minimal changes in …