The increasing threat of Pseudomonas aeruginosa high-risk clones

A Oliver, X Mulet, C López-Causapé, C Juan - Drug Resistance Updates, 2015 - Elsevier
… Due to its impressive metabolic plasticity and versatility, P. … aeruginosa clinical isolates, is
the selection of mutations in … been detected among ST111 isolates (Table 3). Class A ESBLs …

The distributed genome hypothesis as a rubric for understanding evolution in situ during chronic bacterial biofilm infectious processes

…, P Stoodley, JC Post, P DeMeo… - … & Medical …, 2010 - academic.oup.com
… ) have revealed that, on average, each strain contains between … Confocal micrograph of
a Pseudomonas aeruginosa PAO1 … In this study, we identified a dominant strain that, over a …

Dissecting colistin resistance mechanisms in extensively drug-resistant Acinetobacter baumannii clinical isolates

V Trebosc, S Gartenmann, M Tötzl, V Lucchini… - MBio, 2019 - Am Soc Microbiol
… Enterobacteriaceae, MDR Pseudomonas aeruginosa, and … Using these eptA-specific primers,
we detected eptA in all our … baumannii; however, their distribution, expression regulation…

… analyses of a eukaryotic‐like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection …

PJ Wilderman, AI Vasil, Z Johnson… - Molecular …, 2001 - Wiley Online Library
detected PC in both the inner and the outer membrane of P. … aeruginosa PAO1 carries 10
randomly distributed copies of … for genetic variability contribute to genome plasticity through …

Emergence of Carbapenem Resistance Due to the Novel Insertion Sequence ISPa8 in Pseudomonas aeruginosa

RC Fowler, ND Hanson - PLoS One, 2014 - journals.plos.org
… of carbapenem resistance when a clinical isolate of P. … of the oprD gene from PA42
showed 99% similarity to oprD from P. … genomic plasticity and participate in the evolution of P. …

Direct RNA nanopore sequencing of Pseudomonas aeruginosa clone C transcriptomes

MM Pust, CF Davenport, L Wiehlmann… - Journal of …, 2022 - Am Soc Microbiol
aeruginosa clone C, ie, the cystic fibrosis clinical isolate NN2 … share their core genomes and
most regions of plasticity (RGPs)… detected more differences in gene expression between the …

[HTML][HTML] Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review

A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
… requires transitioning clinical isolates from clinical settings to … A number of studies have
revealed genetic and phenotypic … these studies can aid in novel gene target identification to kill …

Diversity and metallo-β-lactamase-producing genes in Pseudomonas aeruginosa strains isolated from filters of household water treatment systems

S Mombini, SE Rezatofighi, L Kiyani… - Journal of environmental …, 2019 - Elsevier
… wide distribution of resistant phenotypes and genetic plasticity … VIM-1 genes are usually
prevalent in clinical isolates of MBL-… genes studied were not detected in MBL-producing isolates. …

Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates

…, RE McLaughlin, E Song, P Warrener… - The Journal of …, 2018 - academic.oup.com
… the outer membrane and extraordinary genetic plasticity [2, 3]… analyses of the clinical
isolates revealed substitutions at 35 … of pcrV gene–negative isolates (n = 11) identified in this …

Two novel class I integron arrays containing IMP-18 metallo-β-lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico

T Martínez, GJ Vazquez, EE Aquino… - Antimicrobial agents …, 2012 - Am Soc Microbiol
… In nine isolates, a class I integron with a novel gene array was identified that contained bla
… No bla IMP-18 -positive isolates were detected in the north and west regions. Only colistin …