… SLC26A4 is the most frequently mutated gene in Pendred syndrome. ► Development of
a … of pendrin Cl − /I − transport were studied by a previously reported fluorometric method, …

… mutations in the SLC26A4 gene, which encodes pendrin, a … its ability to transport iodide
suggest that pendrin may be one … impaired chloride/bicarbonate exchange activity. Each of the …

… transepithelial transport to cell volume regulation and from mediation of neuronal activity …
cells (top panel) and indicates a faster recovery from intracellular acidosis in Slc26a11-…

… modifiers of pendrin activity and on SLC26A4 gene sequence … flux, measurement of
intracellular pH, measurement of … 50 % inhibition of pendrin transport activity in the low micromolar …

… Pendrin (SLC26A4, PDS) is a transport protein whose malfunction or up … that pendrin
activity may influence platelet functions, including volume regulation, intracellular pH, transport of …

… We report that pendrin has transport properties similar to that … PCR from a human thyroid
gland Quick-Clone cDNA library (… can be transported via pendrin, we measured the rate of [ 14 …

… Administration of doxycycline initially enables Slc26a4-null mice to express pendrin at the
exact … Fast fluorometric method for measuring pendrin (SLC26A4) Cl-/I- transport activity. Cell …

… modifiers of pendrin activity and on SLC26A4 gene sequence … and efficacy against
pendrin-dependent Cl−/SCN−, Cl−/ I−, … ) Fast fluorometric method for measuring pendrin (SLC26A4) …

… and nitrate transport. The molecular mechanism for the epithelial-specific activity of pendrin
in … express low levels of pendrin mRNA, indicating that the SLC26A4 mutation is responsible …

… in the PDS/SLC26A4 gene cause the Pendred syndrome, an … above, the cells were quickly
washed with warm PBS. … synthesis and activity is inhibited, while pendrin [Pendred syndrome (…