[HTML][HTML] First-in-human experience with a novel fully bioabsorbable occluder for ventricular septal defect

L Chen, S Hu, Z Luo, G Butera, Q Cao, F Zhang… - Cardiovascular …, 2020 - jacc.org
defects (VSDs) in humans. We describe here a first-in-human experience with the
implantation of a fully bioabsorbable occluder (Figure 1A) for VSDs aided by echocardiographic …

Initial experiences with a novel biodegradable device for percutaneous closure of atrial septal defects: from preclinical study to firstinhuman experience

YF Li, YM Xie, J Chen, BN Li, ZF Xie… - Catheterization and …, 2020 - Wiley Online Library
… The use of completely bioresorbable septal defect occlusion … device, which is made of fully
biodegradable polymers,15 the … , and the Carag bioresorbable septal occluder (Carag AG, …

[HTML][HTML] Transcatheter closure of perimembranous ventricular septal defect using a novel fully bioabsorbable occluder: multicenter randomized controlled trial

S Wang, Z Li, Y Wang, T Zhao, X Mo, T Fan, J Li, T You… - Science Bulletin, 2023 - Elsevier
… 14.81% for the bioabsorbable and nitinol groups, … bioabsorbable occluder group (0/54 vs.
6/54, P = 0.036) at 24-month follow-up. In conclusion, the novel fully bioabsorbable occluder

Biodegradable polymeric occluder for closure of atrial septal defect with interventional treatment of cardiovascular disease

B Li, Z Xie, Q Wang, X Chen, Q Liu, W Wang, Y Shen… - Biomaterials, 2021 - Elsevier
… Pan et al. reported first-in-human experience with a novel fully bioabsorbable occluder
for ventricular septal defect (VSD) and 6-month follow-ups [76]. The framework of their …

A fully degradable transcatheter ventricular septal defect occluder: Towards rapid occlusion and post-regeneration absorption

G Guo, J Hu, F Wang, D Fu, R Luo, F Zhang, C Hu… - Biomaterials, 2022 - Elsevier
… The first-in-human study of our degradable occluder has been reported by Pan [51]. The …
2022, which became the first bioresorbable cardiac occluder approved by national regulatory …

Interventional atrial septal defect closure using a totally bioresorbable occluder matrix: development and preclinical evaluation of the BioSTAR device

C Jux, H Bertram, P Wohlsein, M Bruegmann… - Journal of the American …, 2006 - jacc.org
fully retrievable occluder framework. This research may eventually result in various totally
bioresorbable … , the first in human investigation of this new technology, has been scheduled. …

[HTML][HTML] Favorable mid-term performance of fully biodegradable implantable device for ventricular septal defect closure

S Song, Z Shao, T Fan, B Li, W Liang, H Dong, K Wu… - JTCVS …, 2023 - Elsevier
… Use of a novel, fully biodegradable occluder for this purpose has … of a novel, fully biodegradable
occluder to address … initial results of a fully bioabsorbable occluder (Shanghai Shape …

[HTML][HTML] A fully biodegradable polydioxanone occluder for ventricle septal defect closure

Z Li, P Kong, X Liu, S Feng, W Ouyang, S Wang, X Hu… - Bioactive Materials, 2023 - Elsevier
… Collectively, the fully bioresorbable PDO occluder is safe and … we developed a novel fully
biodegradable PDO occluder. To … At last, the pilot first-in-human trial confirmed the feasibility …

Recent developments in next-generation occlusion devices

C Lin, L Liu, Y Liu, J Leng - Acta Biomaterialia, 2021 - Elsevier
… (PDA), and ventricular septal defect (VSD). Advancements in … There are a variety of novel
biodegradable occluders using … Besides, the frame of the Carag bioresorbable septal occluder (…

[HTML][HTML] Recent Development of Biodegradable Occlusion Devices for Intra-Atrial Shunts

YF Li, ZW Chen, ZF Xie, SS Wang, YM Xie… - Reviews in …, 2024 - imrpress.com
… from “partially bioabsorbable” to “fully bioabsorbable”. A … /collagen occluder is a novel
biodegradable ASD occlusion … Based on these promising preclinical results, the first-in-human