… In a study of 21 men with prostate biopsies showing PIN but … in a randomized, double
blind, placebo-controlled prevention … basis with combined flutamide and luteinizing hormone-…

… prostatic intraepithelial neoplasia (PIN) and prostate cancer … 250 mg/d versus placebo or
a combination of flutamide and … randomised, double-blind, placebo-controlled phase 2b trial …

… -grade prostatic intraepithelial neoplasia. Cyclooxygenase-2 activity has been linked with …
study (ATBC study) was a double-blind, randomised, placebo-controlled trial of 29 133 male …

… number of men living with early stages of prostate cancer is expected … In contrast, high grade
prostatic intraepithelial neoplasia (… in randomised placebo-controlled trials. At present, these …

… A reduction in dose (eg, flutamide at 250 mg given once daily … prostatic intraepithelial
neoplasia in radical prostatectomy … randomized, double-masked, placebo-controlled trials with …

… be considered for prostate cancer chemoprevention trials, due to … with another nonsteroidal
antiandrogen, flutamide (300 mg). The … [12] in their prospective, placebo-controlled study of …

… prostatic intraepithelial neoplasia (HGPIN) to locally invasive … This landmark randomized,
placebo-controlled trial … flutamide decreased both ODC activity and growth of human DU-145 …

… A placebo-controlled randomized trial using finasteride, an inhibitor of the enzyme that
converts testosterone to … The endpoint of this trial will be reduction of prostate cancer incidence. …

… -carotene Cancer Prevention study in a placebo controlled, … of prostatic adenocarcinoma
in men with HGPIN. A clinical … of flutamide in patients with prostatic intraepithelial neoplasia. …

… Prostatic intraepithelial neoplasia (PIN) can be used as a … The other cohorts are men with
prostate cancer for … randomized, double-blinded and placebo-controlled. Some Phase I …