Animal models for treating spinal cord injury using biomaterials-based tissue engineering strategies

JJ Li, H Liu, Y Zhu, L Yan, R Liu, G Wang… - … Engineering Part B …, 2022 - liebertpub.com
… Significantly reduced injury-induced demyelination and … rat NSCs Significantly improved
locomotion recovery; grafted … gradually in rats within 8 weeks, after which functional scores …

[HTML][HTML] Mesenchymal stem cells in treatment of spinal cord injury and amyotrophic lateral sclerosis

E Sykova, D Cizkova, S Kubinova - Frontiers in cell and …, 2021 - frontiersin.org
… , including human decellularized extracellular matrix (ECM) or … of a rat spinal cord with acute
balloon-induced spinal cord … the improvement of the hind limb function and bladder control. …

Traumatic spinal cord injury

CS Ahuja, JR Wilson, S Nori, M Kotter… - Nature reviews Disease …, 2017 - nature.com
… the spinal cord can result in partial or complete loss of function … proliferate and deposit
extracellular matrix molecules into the … Rat models are the most commonly used for SCI research …

[HTML][HTML] … effect of collagen and fibrin hydrogels encapsulated with adipose tissue mesenchymal stem cell-derived exosomes for treatment of spinal cord injury in a rat …

Z Afsartala, M Hadjighassem, S Shirian… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
… ( 5 - 10 ), effective functional recovery has yet to be introduced. … , damage of the extracellular
matrix, and hypoxic ischemia is … for the treatment of nerve injury-induced pain in rats ( 54 ). …

Perspectives in the cell-based therapies of various aspects of the spinal cord injury-associated pathologies: Lessons from the animal models

M Zawadzka, A Kwaśniewska, K Miazga, U Sławińska - Cells, 2021 - mdpi.com
… In the rat model of spinal cord compression, grafting … cells, leading to functional recovery of
grafted animals manifested by … However, the injury-induced secretome was produced within a …

Human urinary bladder regeneration through tissue engineering–an analysis of 131 clinical cases

M Pokrywczynska, J Adamowicz… - Experimental …, 2014 - journals.sagepub.com
… pericardium as a graft material for bladder augmentation. … studies are required especially
to achieve functional bladder. … from patients with the neurogenic bladder can be effectively …

Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials

CM Zipser, JJ Cragg, JD Guest, MG Fehlings… - The Lancet …, 2022 - thelancet.com
rat models of stroke, cortical ablation, parkinsonism and … related to the cell transplant or
the intramedullary injection … improvements in fine motor function when assessed using the …

Single-walled carbon nanotubes chemically functionalized with polyethylene glycol promote tissue repair in a rat model of spinal cord injury

JA Roman, TL Niedzielko, RC Haddon… - Journal of …, 2011 - liebertpub.com
… repair, axonal regrowth, and functional recovery in a rat model of SCI. … of PEG reduces
injury-induced tissue cavitation and … channels grafted into transected adult rat spinal cordJ. Comp…

[HTML][HTML] Multiple strategies enhance the efficacy of MSCs transplantation for spinal cord injury

QM Pang, KQ Deng, M Zhang, XC Wu, RL Yang… - Biomedicine & …, 2023 - Elsevier
… the normal physiological structure of rat spinal cord tissue (A) … GDNF Improve
neovascularization and extracellular matrix … promote the functional recovery of hindlimbs in SCI …

Development of a porcine bladder acellular matrix with well-preserved extracellular bioactive factors for tissue engineering

B Yang, Y Zhang, L Zhou, Z Sun, J Zheng… - … Engineering Part C …, 2010 - liebertpub.com
… Tanagho EAThe bladder acellular matrix graft in a rat chemical cystitis … Functional improvement
in spinal cord injury-induced neurogenic bladder by bladder augmentation using bladder