… AMPA receptor activation is necessary for the antidepressant … the ketamine-induced activation
of the mammalian target of … of GSK-3 inhibition in the antidepressant effects of ketamine …

… target of rapamycin (mTOR) pathway which also leads to … Increased phosphorylation of
GSK-3 induced by ketamine is … a glutamate surge; increased activation of the AMPA receptor in …

… effect of ketamine, and that ketamine may result in rapid antidepressant effect by enhancing
AMPA relative to NMDA … and indirect effects on GSK-3, and GSK-3-regulated cell signaling …

… populations/brain areas in the regulation of mood. Altogether, … Additionally, the enhancement
of GluA1 AMPA receptor (… data analyzing the antidepressant effect of ketamine from the …

… -throughput transcriptome sequencing to investigate the molecular mechanisms regulating
the effects of lithium on ketamine… potential drug targets for the lithium- and/or ketamine-treated …

… drug, with the aim of assessing longer‐term effects. In all the … Evidence for the mediating
role of AMPA receptors includes … kinase‐3 (GSK‐3), one of the suggested mechanisms for the …

… ketamine blocks NMDA receptors on inhibitory neurons, leading to increased extracellular
glutamate, activation of AMPA … in mood regulation. We hypothesize that this combination could …

… and potential downstream targets of GSK-3 that may contribute to … Thus, in this review,
increased activation of GSK-3 coincident with … Recently, ketamine has been of particular inte…

… is that the rapid glutamate burst and AMPA receptor-mediated … actions of ketamine are
also mediated by regulation of SST … as a target of ketamine as constitutive NMDA receptor …

… α5 positive allosteric modulator of α5 GABAA receptors AMPA … ketamine’s antidepressant
effects, we aim to determine whether the three … anesthesia on cognitive performance. …