CD146/MCAM links doxorubicin-induced epigenetic dysregulation to the impaired fatty acid transportation in H9c2 cardiomyoblasts
AU Hasan, M Obara, S Sato, Y Kondo… - … and Biophysical Research …, 2024 - Elsevier
… ), MUC18, or Gicerin, is encoded by the MCAM gene. For … CD146 acts as a cell surface
receptor facilitating the binding of its pro-malignant and proangiogenic ligands, such as galectin-3 …
receptor facilitating the binding of its pro-malignant and proangiogenic ligands, such as galectin-3 …
[HTML][HTML] Elements of the endomucin extracellular domain essential for VEGF-induced VEGFR2 activity
… for vascular endothelial growth factor (VEGF)-induced VEGF … glycosylation causes EMCN
to project rigidly from the cell surface, … , galectin-3 binds to N-linked glycans on CD146/MCAM (…
to project rigidly from the cell surface, … , galectin-3 binds to N-linked glycans on CD146/MCAM (…
[HTML][HTML] Cancer combination therapies by angiogenesis inhibitors; a comprehensive review
MJ Ansari, D Bokov, A Markov, AT Jalil… - Cell Communication and …, 2022 - Springer
… The main targets included vascular endothelial growth factor … induces angiogenesis in
tumor cells following interaction … functions of cytokine-induced killer cells (CIK cells) cells by …
tumor cells following interaction … functions of cytokine-induced killer cells (CIK cells) cells by …
[HTML][HTML] Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells
L Seguin, S Odouard, F Corlazzoli, SA Haddad… - Communications …, 2021 - nature.com
… involved the carbohydrate-binding protein Galectin-3 (Gal-3) … by directly binding to the cell
surface receptor integrin αvβ3, we … MCAM, also known as MUC18 or CD146, is upregulated in …
surface receptor integrin αvβ3, we … MCAM, also known as MUC18 or CD146, is upregulated in …
[HTML][HTML] MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β1-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration
L Zondler, S Herich, P Kotte, K Körner… - Frontiers in …, 2020 - frontiersin.org
… Melanoma cell adhesion molecule (MCAM; CD146, MUC18) … For labeling of cell surface
molecules and subsequent FAC … by pro-inflammatory cytokines such as TNFα and IL1α (52) …
molecules and subsequent FAC … by pro-inflammatory cytokines such as TNFα and IL1α (52) …
[HTML][HTML] Unraveling how tumor-derived galectins contribute to anti-cancer immunity failure
DJ Laderach, D Compagno - Cancers, 2021 - mdpi.com
… extracellular galectin-3 induces apoptosis in human T cells … to secrete killing cytokines (even
while these cells produce … isomerase (PDI) at the cell surface, thus controlling the redox …
while these cells produce … isomerase (PDI) at the cell surface, thus controlling the redox …
CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases
B Xue, P Wang, W Yu, J Feng, J Li, R Zhao… - Science China Life …, 2022 - Springer
… Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and
induces secretion of metastasis-promoting cytokines from vascular endothelial …
induces secretion of metastasis-promoting cytokines from vascular endothelial …
[HTML][HTML] Increased serum levels of Galectin‑9 in patients with chronic lymphocytic leukemia
K Wdowiak, E Gallego‑Colon, T Francuz… - Oncology …, 2019 - spandidos-publications.com
… galectin binding to specific cell surface receptors, activating … Galectins induce the secretion
of cytokines and chemokines, … -9, (C) galectin-3 and (D) galectin 3-binding protein in …
of cytokines and chemokines, … -9, (C) galectin-3 and (D) galectin 3-binding protein in …
Expression and Clinical Significance of Galcetin-3 in the Serum of Non-small Cell Lung Cancer Patients
QI Delin, Y Zhang, LI Hongli, W Ruotian… - Zhongguo Fei Ai Za …, 2020 - search.proquest.com
… Galectin-3 interacts with the cellsurface glycoprotein CD146 (MCAM, MUC18) and
induces secretion of metastasis-promoting cytokines from vascular endothelial …
induces secretion of metastasis-promoting cytokines from vascular endothelial …