… as an independent peripheral T-cell lymphoma (PTCL) entity. … in PTCL (chidamide, pralatrexate,
idelalisib, and TGR1202), … Finally, pre-clinical HTS using IL89 revealed a potential new …

… HLs shows localized spread from one lymph node to another … due to the generation of
multiple drug resistance. Repeated … T cell lymphoma with leukemic manifestations Pro-drug …

… SS), the most common types of cutaneous T-cell lymphoma (CTCL), … Acquired resistance
may occur despite initial responses, and … This analysis revealed a significant inverse correlation …

… useful as the next generation of diagnostic biomarkers for the … risk assessment of CML
revealed that epigenetic alterations, … or peripheral T-cell lymphoma, and phase 1/2 trials on …

… 85% of ALL arise from the B cell lineage and 15% from T cell … This interaction can also
lead to drug resistance [39,41]. The … with a favorable prognosis of multiple types of HM [44,…

… the roles of epigenetic modifiers not only reveals the various … IL-2 receptor marker CD25
and the T-cell activation marker … HDAC inhibitors have been shown to inhibit the generation of …

… types of aggressive B- and T-cell non-Hodgkin's lymphomas (… Growth factors generating
malignant stromal response that … SMIs active in PTCL include folate analog pralatrexate, 63 …

… There are three latency states expressing unique patterns of … in the epigenetic treatment of
T-cell prolymphocytic leukemia (T-… cytometry reveals prolymphocytes with post-thymic T-cell …

… lymphoma revealed marked activity in patients with T cell … Pralatrexate (pdx) produces a
high and durable complete … in patients with chemotherapy resistant t-cell lymphomas. Annals of …

… T-cell lymphoma (CTCL) [1], belinostat for refractory peripheral … Early structural studies in
HDAC-8 revealed the mode of … Generation of ROS was shown to happen as early as 2 hours …