… , Kain KC: Genetic confirmation of atovaquoneproguanil-resistant Plasmodium falciparum
malaria acquired by a nonimmune traveler to East Africa. Clin Infect Dis 2003, 37:450-451. 27. …

… transmission characterized by a non-immune population with high … falciparum Pfmdr 1
gene and at codon 76 of the P. … Furthermore, costly acquisition of immunity in the resident …

… be as high as 0.6–3.6% in nonimmune travelers, as reported by the … Travelers acquiring the
infection during travel may be … Plasmodium falciparum malaria is the leading travel-related …

… specifically targets Plasmodium falciparum cytochrome b (Pfcytb), a mitochondrial gene with
… ], or in travellers returning to France from West and Central Africa [40]. As observed in other …

… Genetic sequencing data have revealed that the genes encoding … antimalarial for people
traveling to these endemic areas. … need to be acquired through de novo biosynthetic pathways. …

… Genetic confirmation of atovaquone-proguanil resistant Plasmodium falciparum malaria
acquired by a nonimmune traveler to East Africa. Clin Infect Dis 2003; 37: 450–1. …

… of genetically confirmed clinical resistance to AP have been reported in travelers returning
from West, Central and East Africa … Although not specifically studied in nonimmune travelers, …

… disease but are more powerful to confirm the presence of P. … endemicity than for nonimmune
febrile returned travelers (28)… Plasmodium falciparum malaria acquired by a non-immune …

… genetic variation within the parasite population is gained. This article will consider genetic
variation in the malaria … of the genetic basis of resistance in Plasmodium falciparum has been …

… also for prevention of malaria in healthy travelers, tens of millions of … falciparum genes and
their expression is available on the … ), and even to the acquisition of foreign DNA. Alterations in …