Genome-wide linkage scan of quantitative traits representing symptom dimensions in multiplex schizophrenia families
… of disease-susceptibility genes, or separate traits related to disease-modifier genes. …
symptom dimensions of schizophrenia through genome-wide quantitative trait locus (QTL) linkage …
symptom dimensions of schizophrenia through genome-wide quantitative trait locus (QTL) linkage …
Heritability of subcortical and limbic brain volume and shape in multiplex-multigenerational families with schizophrenia
… use of multiplex-multigenerational families is likely to represent a … multiplex-multigenerational
families with schizophrenia. Such localized features may be related to distinct dimensions …
families with schizophrenia. Such localized features may be related to distinct dimensions …
Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders
… Second, genome-wide association studies (GWAS) were … As demonstrated by twin and family
studies, each of the disorders has a … Bipolar multiplex families have an increased burden of …
studies, each of the disorders has a … Bipolar multiplex families have an increased burden of …
The multidimensionality of schizotypy in nonpsychotic relatives of patients with schizophrenia and its applications in ordered subsets linkage analysis of schizophrenia
YJ Lien, HC Tsuang, A Chiang, CM Liu… - American Journal of …, 2010 - Wiley Online Library
… among the relatives from multiplex schizophrenia families. … Our previous genome-wide
linkage analysis reported that … be to conduct a quantitative trait locus (QTL) linkage analysis of …
linkage analysis reported that … be to conduct a quantitative trait locus (QTL) linkage analysis of …
A quantitative trait locus analysis of social responsiveness in multiplex autism families
JA Duvall, A Lu, RM Cantor, RD Todd… - American Journal of …, 2007 - Am Psychiatric Assoc
… Alzheimer’s disease and schizophrenia is about 0.45% and … genome-wide linkage scan for
social quantitative trait loci in … research represents the first genome scan of core social traits …
social quantitative trait loci in … research represents the first genome scan of core social traits …
A genome‐wide quantitative trait locus (QTL) linkage scan of NEO personality factors in Latino families segregating bipolar disorder
BD Lee, S Gonzalez, E Villa… - American Journal of …, 2017 - Wiley Online Library
… extended pedigrees originally ascertained for having multiplex cases of BP (963 cases of …
genome-wide suggestive cutoff (LOD scores >2.2) as determined for each triat are represented …
genome-wide suggestive cutoff (LOD scores >2.2) as determined for each triat are represented …
[HTML][HTML] Genome-wide linkage analyses of quantitative and categorical autism subphenotypes
XQ Liu, AD Paterson, P Szatmari… - Biological …, 2008 - Elsevier
… In this study, using 976 multiplex families from the Autism … both ASD and schizophrenia, for
example, association of gene … to different dimensions, so the quantitative traits we used may …
example, association of gene … to different dimensions, so the quantitative traits we used may …
Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q
T Paunio, A Tuulio-Henriksson… - Human molecular …, 2004 - academic.oup.com
… , we analyzed genome-wide data for 168 schizophrenia families … In the present study, we
investigated a set of quantitative trait … sets of 90 Irish multiplex schizophrenia families and follow-…
investigated a set of quantitative trait … sets of 90 Irish multiplex schizophrenia families and follow-…
A genome-wide linkage scan for distinct subsets of schizophrenia characterized by age at onset and neurocognitive deficits
YJ Lien, PC Hsiao, CM Liu, SV Faraone, MT Tsuang… - PloS one, 2011 - journals.plos.org
… may reduce heterogeneity or represent the more direct effects of … of families of patients with
schizophrenia characterized by … sub-grouping by particular quantitative traits in these studies. …
schizophrenia characterized by … sub-grouping by particular quantitative traits in these studies. …
Genome-wide association studies for common diseases and complex traits
JN Hirschhorn, MJ Daly - Nature reviews genetics, 2005 - nature.com
… common diseases and related quantitative traits. This strategy … The genome-wide association
approach therefore represents … , family-based and haplotype-based tests of association for …
approach therefore represents … , family-based and haplotype-based tests of association for …